咽囊来源的癌。
Carcinoma arising from pharyngeal diverticula.
机构信息
Head and Neck Unit, Royal Marsden Hospital, London, SW3 6JJ, United Kingdom.
出版信息
Head Neck. 2011 Jan;33(1):135-7. doi: 10.1002/hed.21259.
BACKGROUND
Pharyngeal diverticulum or Zenker's diverticulum carcinoma is a rare malignancy with a poor prognosis. Carcinoma arising in a recurrent pharyngeal diverticulum is even rarer, with only 1 such case reported in the English-language literature. We report 2 patients with pharyngeal diverticulum carcinoma exhibiting an unusual presentation and good long-term, disease-free survival with normal speech and swallowing.
METHODS
A 70-year-old man with a carcinoma in a recurrent pharyngeal diverticulum excised 20 years previously and a 65-year-old man with a neck mass as the only presentation of pharyngeal diverticulum carcinoma.
RESULTS
Our patients were treated with open resection, laryngeal preservation, and postoperative radiotherapy (PORT), resulting in long-term tumor control and disease-free survival of 5 and 15 years (longest reported), respectively.
CONCLUSION
One-stage diverticulectomy with or without radiotherapy is the treatment of choice and can provide long-term control and survival.
背景
咽囊或 Zenker 憩室癌是一种预后不良的罕见恶性肿瘤。在复发性咽囊发生的癌更为罕见，在英语文献中仅报告过 1 例。我们报告了 2 例咽囊癌患者，他们的表现不寻常，且长期无病生存，言语和吞咽功能正常。
方法
1 例 70 岁男性，20 年前曾行复发性咽囊癌切除术，1 例 65 岁男性以颈部肿块为唯一表现的咽囊癌。
结果
我们的患者接受了开放性切除术、喉保留和术后放疗（PORT），分别获得了长达 5 年和 15 年（最长报告）的长期肿瘤控制和无病生存。
结论
一期憩室切除术加或不加放疗是治疗的首选方法，可以提供长期的控制和生存。
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