来自南极苔藓虫属 Aplidium 物种的具有生物活性的混合倍半萜类化合物 Rossinones A 和 B。
Rossinones A and B, biologically active meroterpenoids from the Antarctic ascidian, Aplidium species.
机构信息
Department of Chemistry, The University of Auckland, Private Bag 92019, Auckland, New Zealand.
出版信息
J Org Chem. 2009 Dec 4;74(23):9195-8. doi: 10.1021/jo901846j.
PMID:19863121
Abstract
Rossinones A (1) and B (2), biologically active meroterpene derivatives, were isolated from an Antarctic collection of the ascidian Aplidium species and structurally characterized with spectroscopic methods. The absolute configuration of 1 was deduced by using the modified Mosher method. The rossinones exhibit anti-inflammatory, antiviral and antiproliferative activities.
摘要
罗辛酮 A（1）和 B（2）是从南极采集的 Aplidium 种属中分离出的具有生物活性的混合萜类衍生物，并通过光谱方法进行了结构鉴定。1 的绝对构型通过改进的 Mosher 方法推断。罗辛酮具有抗炎、抗病毒和抗增殖活性。
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