铂催化乙烯基硅烷在β位的亲核加成反应。

Platinum-catalyzed nucleophilic addition of vinylsilanes at the beta-position.

作者信息

Miura Katsukiyo, Inoue Gen, Sasagawa Hisashi, Kinoshita Hidenori, Ichikawa Junji, Hosomi Akira

机构信息

Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University, Sakura-ku, Saitama 338-8570, Japan.

出版信息

Org Lett. 2009 Nov 5;11(21):5066-9. doi: 10.1021/ol902060r.

DOI:10.1021/ol902060r

PMID:19863155

Abstract

In the presence of catalytic amounts of PtCl(2) and metal iodides, beta-substituted vinylsilanes reacted with aldehydes at the beta-position to give allyl silyl ethers. The Pt-catalyzed addition to aromatic aldehydes proceeded efficiently in the presence of LiI. The combined use of PtCl(2) and MnI(2) was found to be effective in addition to aliphatic aldehydes.

摘要

在催化量的PtCl(2)和金属碘化物存在下，β-取代的乙烯基硅烷在β位与醛反应生成烯丙基硅基醚。在LiI存在下，Pt催化的与芳香醛的加成反应高效进行。发现PtCl(2)和MnI(2)的联合使用对于与脂肪醛的加成反应也是有效的。