Leclerc Jacques E, Leclerc Jean Thomas
Department of Otolaryngology - Head & Neck Surgery, Laval University, Quebec City, Canada.
Int J Pediatr Otorhinolaryngol. 2009 Dec;73(12):1746-50. doi: 10.1016/j.ijporl.2009.09.031. Epub 2009 Oct 27.
To study the growth and size of the sphenoid sinuses in choanal atresia patients.
Case-control single blinded retrospective study.
Fifteen non-syndromic patients (ages 0-26 years old) were selected because they had at least one suitable CT scan (nine bilateral and 11 unilateral=total 20 scans). Twenty age-matched CT scans were used as controls. The following linear measurements were obtained: (1) fronto-zygomatic width, (2) zygomatic width, (3) width of the maxillary sinuses, (4) width of the sphenoid sinuses. Statistical analysis was performed with the exact permutation test in the framework of a parametric analysis of a randomized completed block.
The width measurements of the choanal atresia CT scans did not show any statistically significant difference when compared to their control CT scans except for the zygomatic width in the bilateral choanal atresia patients. In the latter, the width was smaller (p=0.03).
In unilateral and bilateral choanal atresia patients, there is normal growth of the width of the sphenoid sinuses.
研究后鼻孔闭锁患者蝶窦的生长和大小。
病例对照单盲回顾性研究。
选择15例非综合征型患者（年龄0 - 26岁），因为他们至少有一次合适的CT扫描（9例双侧，11例单侧，共20次扫描）。选取20例年龄匹配的CT扫描作为对照。进行了以下线性测量：（1）额颧宽度，（2）颧宽度，（3）上颌窦宽度，（4）蝶窦宽度。在随机完全区组参数分析框架内，采用精确排列检验进行统计分析。
与对照CT扫描相比，后鼻孔闭锁CT扫描的宽度测量除双侧后鼻孔闭锁患者的颧宽度外，均未显示出任何统计学上的显著差异。在后者中，宽度较小（p = 0.03）。
在单侧和双侧后鼻孔闭锁患者中，蝶窦宽度生长正常。
