Baillot Richard G, Joanisse Denis R, Stevens Louis Mathieu, Doyle Daniel P, Dionne Brigitte, Lellouche François
Department of Cardiac Surgery, Institut Universitaire de Cardiologie et dePneumologie de Québec, Hôpital Laval, Québec, Que.
Can J Surg. 2009 Oct;52(5):394-400.
Over the last 12 years, the demographic and clinical characteristics of patients undergoing myocardial revascularization surgery have evolved rapidly. The goal of our study was to analyze the evolution of these trends and the results of these surgical interventions.
We identified patients who underwent a first or second myocardial revascularization between 1993 and 2004, and we arbitrarily divided them into 2 groups: 1 cohort of patients who underwent surgery between 1993 and 1998 and 1 cohort of patients who underwent surgery between 1999 and 2004. We compared demographic and clinical characteristics between the 2 cohorts and determined which variables were significant predictors of morbidity and mortality.
From 1993 to 2004, 12 202 patients underwent a first (95.5%) or second (4.5%) myocardial revascularization. Patients in the later cohort presented with a high-risk profile. They were older and had metabolic syndrome or diabetes and peripheral vascular disease. On the other hand, there were fewer active smokers in this group. Whereas the rate of postoperative infarction and renal insufficiency was higher in the second cohort, this group had a lower incidence of stroke and prolonged mechanical ventilation and shorter hospital stays. Overall, observed mortality decreased in spite of a steady increase in predicted mortality. Identified predictors of mortality were age, stroke, female sex, nonelective surgery, renal insufficiency, peripheral vascular disease, chronic obstructive pulmonary disease, ventricular dysfunction and stenosis of the left main trunk.
Our study confirmed current trends that show an increase in the at-risk population with dysmetabolic syndrome in cardiac surgery, as well as constant improvements in tertiary care in anesthesia and coronary surgery.
在过去12年中,接受心肌血运重建手术患者的人口统计学和临床特征迅速演变。我们研究的目的是分析这些趋势的演变以及这些手术干预的结果。
我们确定了在1993年至2004年间接受首次或二次心肌血运重建的患者,并将他们任意分为2组:一组是在1993年至1998年间接受手术的患者,另一组是在1999年至2004年间接受手术的患者。我们比较了两组患者的人口统计学和临床特征,并确定哪些变量是发病率和死亡率的重要预测因素。
从1993年到2004年,12202例患者接受了首次(95.5%)或二次(4.5%)心肌血运重建。后一组患者具有高危特征。他们年龄较大,患有代谢综合征或糖尿病以及外周血管疾病。另一方面,该组中的现吸烟者较少。虽然第二组患者的术后梗死和肾功能不全发生率较高,但该组的中风、机械通气延长发生率较低,住院时间较短。总体而言,尽管预测死亡率稳步上升,但观察到的死亡率却有所下降。确定的死亡预测因素包括年龄、中风、女性、非择期手术、肾功能不全、外周血管疾病、慢性阻塞性肺疾病、心室功能障碍和左主干狭窄。
我们的研究证实了当前的趋势,即心脏手术中代谢综合征高危人群增加,以及麻醉和冠状动脉手术的三级护理不断改善。