Department of Surgery, Chirurgia Generale B, Policlinico GB Rossi, University of Verona, Piazzale LA Scuro 10, 37134, Verona, Italy.
J Hepatobiliary Pancreat Sci. 2010 Nov;17(6):782-7. doi: 10.1007/s00534-009-0224-1. Epub 2009 Oct 29.
BACKGROUND/PURPOSE: In recent years there has been an increase in the indications for pancreatic resection of benign or low-grade malignant lesions, especially in young patients with long life expectancy. In this setting, patients may benefit from parenchyma-sparing resections in order to decrease the risk of development of exocrine/endocrine insufficiency.
A review of the literature and authors experience was undertaken.
Parenchyma-sparing resections of the pancreas including enucleation, middle pancreatectomy (MP) and middle-preserving pancreatectomy are described. Short and long-term outcomes after surgery are analyzed with special regard to postoperative morbidity/mortality, and oncological and functional long-term results.
Parenchyma-sparing resections are safe and effective procedures for treatment of benign and low-grade malignant neoplasms. Despite a significant postoperative morbidity they are associated with good long-term functional and oncological results. Enucleation should preferentially be performed laparoscopically whenever possible.
背景/目的：近年来，胰腺良性或低级别恶性病变的切除术适应证有所增加，尤其是在预期寿命较长的年轻患者中。在这种情况下，为了降低发生外分泌/内分泌功能不全的风险，患者可能受益于保留胰腺实质的切除术。
对文献和作者经验进行了回顾。
描述了胰腺保留实质的切除术，包括剜除术、胰体中段切除术（MP）和胰体中段保留切除术。分析了手术后的短期和长期结果，特别关注术后发病率/死亡率以及肿瘤学和功能长期结果。
对于良性和低级别恶性肿瘤，保留胰腺实质的切除术是安全有效的治疗方法。尽管术后发病率较高，但它们与良好的长期功能和肿瘤学结果相关。只要有可能，剜除术应优先在腹腔镜下进行。
