Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8510, Japan.
J Hepatobiliary Pancreat Sci. 2010 Nov;17(6):803-7. doi: 10.1007/s00534-009-0222-3. Epub 2009 Nov 12.
A middle pancreatectomy (MP) is a parenchyma-preserving procedure for benign or low-malignant neoplasms in the neck or body of the pancreas that reduces long-term endocrine and exocrine insufficiency. MP requires the handling of 2 (distal and proximal) pancreatic remnants, and therefore, the higher rates of pancreatic fistula and morbidity may occur after MP rather than after standard pancreatectomies, such as for a pancreaticoduodenectomy and distal pancreatectomy. Though there have so far been few reports regarding a high number of series in MP as opposed to standard pancreatic resections, recently reports describing more than 50 case outcomes of MP were published.
A literature search, which examined articles related to MP, was performed using the PubMed database. Data were compiled to generate conglomerate results of mortality and morbidity rates, and the long-term pancreatic functional insufficiency and recurrence after MP.
The mortality rates varied from 0 to 3%, and the morbidity from 13 to 62%. The rates of pancreatic fistula in more than 50 cases of MP varied from 8 to 30%. The rates of endocrine and exocrine insufficiency were very low (range, 0-9% and 0-8%, respectively).
MP is a safe procedure for the treatment of benign or low-grade malignant neoplasms in the pancreatic neck or body, and in this procedure, the postoperative endocrine and exocrine functions are well preserved.
中胰切除术（MP）是一种保留胰腺实质的手术，适用于胰腺颈部或体部的良性或低度恶性肿瘤，可减少长期内分泌和外分泌不足。MP 需要处理 2 个（远端和近端）胰腺残端，因此，与标准的胰切除术（如胰十二指肠切除术和胰体尾切除术）相比，MP 后发生胰瘘和并发症的几率更高。虽然目前关于 MP 的大量系列报道相对较少，但最近已经有描述超过 50 例 MP 结果的报道。
使用 PubMed 数据库对与 MP 相关的文章进行文献检索。汇总死亡率和发病率以及 MP 后长期胰腺功能不全和复发的数据。
死亡率从 0 到 3%不等，发病率从 13 到 62%不等。MP 超过 50 例的胰瘘发生率从 8 到 30%不等。内分泌和外分泌功能不全的发生率非常低（分别为 0-9%和 0-8%）。
MP 是治疗胰腺颈部或体部良性或低度恶性肿瘤的安全手术，在此手术中，术后内分泌和外分泌功能得到很好的保留。
