Department of Physiology and Pharmacology and the Hospital of The Rockefeller Institute for Medical Research, New York.
J Exp Med. 1913 Oct 1;18(4):450-60. doi: 10.1084/jem.18.4.450.
Electrocardiographic examination of rabbits during the anaphylactic reaction revealed marked and various changes of the heart's activity in twenty-two out of twenty-four animals. Changes occurred in fatal as well as in non-fatal cases, after the vagi were cut as well as when they were intact. Cardiac disturbances are thus a practically constant result of serum anaphylaxis in the rabbit. It therefore is possible that anaphylaxis plays a role in the causation of certain cardiac derangements in man.
在过敏性反应期间对兔子进行心电图检查，发现 24 只动物中有 22 只出现了明显和多种的心脏活动变化。在切断迷走神经后以及迷走神经完好时，无论是致命病例还是非致命病例，都会发生变化。因此，心脏紊乱是兔血清过敏反应的一个实际的恒定结果。因此，过敏反应可能在人类某些心脏紊乱的病因中起作用。
