伤口愈合：I. 伤口大小与愈合速度的关系。
CICATRIZATION OF WOUNDS : I. THE RELATION BETWEEN THE SIZE OF A WOUND AND THE RATE OF ITS CICATRIZATION.
机构信息
Laboratories of The Rockefeller Institute for Medical Research, New York, and Hospital 21, Compiègne, France.
出版信息
J Exp Med. 1916 Nov 1;24(5):429-50. doi: 10.1084/jem.24.5.429.
Abstract
- A method for measuring the area of a wound not geometric in form is described. 2. The rate of cicatrization of a wound is greater at the beginning than at the end of the period of repair. It depends on the area rather than on the age of the wound. There is a constant relation between the size of a wound and the rate of cicatrization. The larger the wound the greater is the rate of cicatrization. Two wounds of different size have a tendency to become equal. 3. The rate is proportional to the area, but diminishes less rapidly than the area. 4. The process of contraction is the more important factor in the repair of a wound. Epidermization completes the work of contraction. After the wound is healed, the cicatrix as a rule expands. 5. The curve representing the diminution of the size of an aseptic wound while it cicatrizes is regular and geometric.
摘要
介绍一种测量非几何形状创面面积的方法。
创面修复的最初阶段比末期阶段的愈合速度更快。愈合速度取决于创面面积而非创面年龄。创面大小与愈合速度之间存在恒定关系，创面越大愈合速度越快。两个不同大小的创面具有趋于相等的趋势。
该速度与面积成正比，但比面积减小得更慢。
收缩过程是创面修复的更重要因素。表皮化完成收缩的工作。创面愈合后，瘢痕通常会扩张。
无菌创面在愈合过程中面积减小的曲线是规则且具有几何形状的。
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