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在丁基羟基茴香醚存在的情况下苯并(a)芘自由基的形成及其在致癌作用中的潜在重要性。

Benzo(a)pyrene free-radicals formation in the presence of butylated hydroxyanisole and their possible importance in carcinogenesis.

作者信息

Krzywanska E, Piekarski L

出版信息

Neoplasma. 1977;24(4):395-400.

PMID:198689
Abstract

By the method of UV irradiation of benzopyrene in the presence of butylated hydroxyanisole, the benzopyrene EPR spectra was investigated and the possible mechanism by which the carcinogenic activity of benzopyrene in the presence of butylated hydroxyanisole is lowered, was studied.

摘要

通过在叔丁基对羟基茴香醚存在下对苯并芘进行紫外线照射的方法，研究了苯并芘的电子顺磁共振光谱，并研究了在叔丁基对羟基茴香醚存在下苯并芘致癌活性降低的可能机制。

相似文献

1
Benzo(a)pyrene free-radicals formation in the presence of butylated hydroxyanisole and their possible importance in carcinogenesis.在丁基羟基茴香醚存在的情况下苯并(a)芘自由基的形成及其在致癌作用中的潜在重要性。
Neoplasma. 1977;24(4):395-400.
2
Short time interval effects of butylated hydroxyanisole on the metabolism of benzo(a)pyrene.丁基羟基茴香醚对苯并(a)芘代谢的短时间间隔效应。
Cancer Res. 1980 Aug;40(8 Pt 1):2824-8.
3
Inhibitory effect of the antioxidant butylated hydroxyanisole on the activation of the carcinogen benzo(a)pyrene.抗氧化剂丁基羟基茴香醚对致癌物苯并(a)芘激活的抑制作用。
Neoplasma. 1979;26(2):139-44.
4
Neoplastic effects of oral administration of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene and their inhibition by butylated hydroxyanisole.口服（±）-反式-7,8-二羟基-7,8-二氢苯并[a]芘的肿瘤效应及其被丁基羟基茴香醚的抑制作用
J Natl Cancer Inst. 1979 Apr;62(4):1103-6.
5
Inhibition in vivo of the formation of adducts between metabolites of benzo(a)pyrene and DNA by butylated hydroxyanisole.丁基羟基茴香醚对苯并(a)芘代谢产物与DNA之间加合物形成的体内抑制作用。
Cancer Res. 1981 Nov;41(11 Pt 1):4309-15.
6
Effects of butylated hydroxyanisole on the metabolism of benzo(a)pyrene by mouse lung microsomes.丁基羟基茴香醚对小鼠肺微粒体代谢苯并(a)芘的影响。
Cancer Res. 1984 Jan;44(1):134-8.
7
Modifications of microsomal and nuclear fractions by butylated hydroxyanisole and its effect on benzo(a)pyrene metabolites binding to macromolecules.丁基羟基茴香醚对微粒体和细胞核组分的修饰及其对苯并(a)芘代谢产物与大分子结合的影响。
Neoplasma. 1984;31(4):423-30.
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Effect of butylated hydroxyanisole on the metabolism of benzo[a]-pyrene and the binding of metabolites to DNA, in vitro and in vivo, in the forestomach, lung, and liver of mice.丁基羟基茴香醚对小鼠前胃、肺和肝脏中苯并[a]芘代谢及其代谢产物与DNA结合的体内外影响。
Carcinogenesis. 1982;3(7):739-45. doi: 10.1093/carcin/3.7.739.
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Benzo(a)pyrene metabolism and metabolites binding to DNA in the presence of BHA.在丁基羟基茴香醚（BHA）存在的情况下，苯并（a）芘的代谢及其代谢产物与DNA的结合。
Arch Geschwulstforsch. 1980;50(4):317-21.
10
Dose-response relationships for the binding of benzo(a)pyrene metabolites to DNA and protein in lung, liver, and forestomach of control and butylated hydroxyanisole-treated mice.对照组和丁基羟基茴香醚处理组小鼠的肺、肝和前胃中苯并(a)芘代谢物与DNA和蛋白质结合的剂量反应关系。
Cancer Res. 1983 Aug;43(8):3712-9.

引用本文的文献

1
Free radicals of benzo(a)pyrene and derivatives.苯并(a)芘及其衍生物的自由基。
Environ Health Perspect. 1985 Dec;64:283-95.