人体全血吞噬肺炎球菌的观察：I. 正常吞噬效价及特异可溶性物质的抗吞噬作用。
OBSERVATIONS ON THE PHAGOCYTOSIS OF THE PNEUMOCOCCUS BY HUMAN WHOLE BLOOD : I. THE NORMAL PHAGOCYTIC TITRE, AND THE ANTI-PHAGOCYTIC EFFECT OF THE SPECIFIC SOLUBLE SUBSTANCE.
机构信息
Department of Bacteriology and Immunology of the Harvard University Medical School, Boston.
出版信息
J Exp Med. 1930 Apr 30;51(5):675-84. doi: 10.1084/jem.51.5.675.
Abstract
- The phagocytic titre of whole human blood against the three types of pneumococcus was determined in a number of individuals. The titre varied over a considerable range in different subjects. 2. Contrary to expectation, the titre in early cases of untreated pneumonia was quite high against the infecting organism, pointing to a local rather than a general lowering of resistance in infection with this organism. 3. Sia's work was confirmed, that the specific carbohydrate has a specific anti-phagocytic action on the blood. This action is more marked in the case of Type III than in Type I.
摘要
对一些个体的全人血针对三种类型的肺炎球菌的吞噬滴度进行了测定。在不同的个体中，滴度变化范围很大。
与预期相反，未经治疗的肺炎早期病例针对感染病原体的滴度相当高，表明在感染这种病原体时局部而不是全身性抵抗力降低。
Sia 的工作得到了证实，即特定的碳水化合物对血液具有特定的抗吞噬作用。这种作用在 III 型比在 I 型更明显。
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