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可溶性特异物质在 II 型和 III 型肺炎球菌口服免疫中的作用。

THE ROLE OF THE SOLUBLE SPECIFIC SUBSTANCE IN ORAL IMMUNIZATION AGAINST PNEUMOCOCCUS TYPES II AND III.

机构信息

Bureau of Laboratories, Department of Health of the City of New York, New York.

出版信息

J Exp Med. 1932 Jan 1;55(1):1-12. doi: 10.1084/jem.55.1.1.

Abstract
  1. When the soluble specific substance of Type II pneumococcus was fed to rats, little or no increased resistance to the organism was obtained. 2. When the specific substance of Type III pneumococcus was fed, an increased resistance to the virulent organism resulted. The percentage of animals protected is smaller than when the whole or the dissolved cell is fed. 3. When the specific polysaccharide of Type I was fed, no immunity against Type II or III was obtained, and the ingestion of the specific substances of Types II and III did not protect rats against the Type I organism.
摘要
  1. 将 II 型肺炎球菌的可溶性特异性物质喂给老鼠时,老鼠对该病原体的抵抗力几乎没有增加。2. 当 III 型肺炎球菌的特异性物质被喂食时,老鼠对毒性生物体的抵抗力增强。受保护动物的百分比比喂食整个或溶解的细胞时要小。3. 当喂食 I 型的特异性多糖时,没有获得针对 II 型或 III 型的免疫力,而且摄取 II 型和 III 型的特异性物质也不能保护老鼠免受 I 型生物体的侵害。

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