Department of Bacteriology, Medical College, National Central University, Woosung, Shanghai, China.
J Exp Med. 1930 May 31;51(6):859-66. doi: 10.1084/jem.51.6.859.
Centrifuge experiments have been carried out with cell-free, active filtrates of vaccinia virus. The experiments have shown that the virus can be concentrated by this method, even in filtrates which have been subjected to prolonged preliminary centrifugation to throw down any inert particles which may have been present in the original filtrate. This fact, together with the knowledge that the virus can be almost completely held back by the Berkefeld N filter, as reported previously (5) indicates that the virus may be of considerable size.
已用无细胞的、活的牛痘病毒滤液进行了离心试验。试验表明,即使是经过长时间初步离心以沉淀原始滤液中可能存在的任何惰性颗粒的滤液,也可用这种方法浓缩病毒。这一事实,加上先前报道(5)的牛痘病毒几乎可以完全被 Berkefeld N 过滤器截留这一事实表明,该病毒的体积可能相当大。