Laboratories of The Rockefeller Institute for Medical Research.
J Exp Med. 1931 Mar 31;53(4):499-510. doi: 10.1084/jem.53.4.499.
Repeated parenteral injections by various routes in a series of twelve rabbits caused an increase of lymphocytes in the peripheral blood varying from 23 per cent to 139 per cent. It seems probable that the degree of response is conditioned upon the type of protein used. At autopsy the lymph nodes and spleen showed hyperplastic changes. The thymus did not participate in the hyperplasia.
在一系列十二只兔子中,通过不同途径反复进行的静脉注射导致外周血淋巴细胞增加 23%至 139%不等。似乎反应的程度取决于所用蛋白质的类型。尸检时,淋巴结和脾脏显示增生性变化。胸腺未参与增生。