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THE INDUCTION OF LYMPHOCYTOSIS AND LYMPHATIC HYPERPLASIA BY MEANS OF PARENTERALLY ADMINISTERED PROTEIN.通过肠外给予蛋白质诱导淋巴细胞增多和淋巴组织增生。
J Exp Med. 1931 Mar 31;53(4):499-510. doi: 10.1084/jem.53.4.499.
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本文引用的文献

1
STUDIES OF THE LYMPHATIC TISSUE : IV. EXPERIMENTAL STUDIES OF THE EFFECT OF THE INTRAVENOUS INJECTION OF KILLED STAPHYLOCOCCI ON THE BEHAVIOR OF LYMPHATIC TISSUE, THYMUS, AND THE VASCULAR CONNECTIVE TISSUE.淋巴组织研究：四、静脉注射灭活葡萄球菌对淋巴组织、胸腺和血管结缔组织行为的实验研究。
J Exp Med. 1929 Feb 28;49(3):361-86. doi: 10.1084/jem.49.3.361.
2
STUDIES OF THE LYMPHATIC TISSUE : III. EXPERIMENTAL STUDIES OF THE RELATION OF THE LYMPHATIC TISSUE TO THE NUMBER OF LYMPHOCYTES IN THE BLOOD IN SUBCUTANEOUS INFECTION WITH STAPHYLOCOCCI.淋巴组织研究：III. 皮下金黄色葡萄球菌感染中淋巴组织与血液中淋巴细胞数量关系的实验研究。
J Exp Med. 1929 Feb 28;49(3):347-60. doi: 10.1084/jem.49.3.347.
3
A STUDY OF THE MECHANISM OF NUCLEINATE-INDUCED LEUCOPENIC AND LEUCOCYTIC STATES, WITH SPECIAL REFERENCE TO THE RELATIVE ROLES OF LIVER, SPLEEN, AND BONE MARROW.核蛋白诱导的白细胞减少症和白细胞减少状态的机制研究，特别参考肝脏、脾脏和骨髓的相对作用。
J Exp Med. 1928 Feb 29;47(3):403-35. doi: 10.1084/jem.47.3.403.
4
THE RHYTHMIC RANGE OF THE WHITE BLOOD CELLS IN HUMAN, PATHOLOGICAL LEUCOPENIC AND LEUCOCYTIC STATES, WITH A STUDY OF THIRTY-TWO HUMAN BONE MARROWS.人类、病理性白细胞减少症和白细胞增多症状态下的白细胞节律范围，对 32 个人类骨髓进行研究。
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5
ARTIFICIAL ACTIVATION OF THE GROWTH IN VITRO OF CONNECTIVE TISSUE.体外结缔组织生长的人工激活。
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通过肠外给予蛋白质诱导淋巴细胞增多和淋巴组织增生。

THE INDUCTION OF LYMPHOCYTOSIS AND LYMPHATIC HYPERPLASIA BY MEANS OF PARENTERALLY ADMINISTERED PROTEIN.

机构信息

Laboratories of The Rockefeller Institute for Medical Research.

出版信息

J Exp Med. 1931 Mar 31;53(4):499-510. doi: 10.1084/jem.53.4.499.

DOI:10.1084/jem.53.4.499
PMID:19869860
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2131984/
Abstract

Repeated parenteral injections by various routes in a series of twelve rabbits caused an increase of lymphocytes in the peripheral blood varying from 23 per cent to 139 per cent. It seems probable that the degree of response is conditioned upon the type of protein used. At autopsy the lymph nodes and spleen showed hyperplastic changes. The thymus did not participate in the hyperplasia.

摘要

在一系列十二只兔子中，通过不同途径反复进行的静脉注射导致外周血淋巴细胞增加 23%至 139%不等。似乎反应的程度取决于所用蛋白质的类型。尸检时，淋巴结和脾脏显示增生性变化。胸腺未参与增生。