Departments of Biological Chemistry and Pathology, College of Physicians and Surgeons, Columbia University, New York.
J Exp Med. 1931 Jul 31;54(2):145-65. doi: 10.1084/jem.54.2.145.
A diet is described, which leads to a progressive, highly selective, and ultimately fatal dystrophy of the voluntary muscles. Guinea pigs and rabbits are susceptible, rats resistant. The diet used is complete in known requirements, except for vitamin E; the addition of this factor, however, does not prevent the development of the disease. The lesions are not due to inanition, infection, or scurvy, and must be referred to some still unknown factor.
有一种饮食会导致进行性、高度选择性且最终致命的自愿性肌肉萎缩症。豚鼠和兔子易感染,而大鼠则具有抗性。所用的饮食在已知需求方面是完整的,除了维生素 E;然而,添加这种因素并不能预防疾病的发展。这些病变不是由于饥饿、感染或坏血病引起的,必须归因于一些尚未知晓的因素。