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胆囊功能的研究:VIII. 胆囊活动对肝胆汁中胆色素和胆固醇的影响。

STUDIES ON GALL BLADDER FUNCTION : VIII. THE FATE OF BILE PIGMENT AND CHOLESTEROL IN HEPATIC BILE SUBJECTED TO GALL BLADDER ACTIVITY.

机构信息

Laboratory of Research Surgery, University of Pennsylvania, Philadelphia.

出版信息

J Exp Med. 1932 Jun 30;56(1):1-11. doi: 10.1084/jem.56.1.1.

Abstract

The data obtained from the experiments on dogs reported in this paper lead us to conclude that bile pigment is not absorbed from the gall bladder bile. The mean loss of pigment is so small when compared with the amount of water lost that it is negligible. Our cholesterol data do not support the concept that this substance is secreted into the gall bladder bile of the dog under normal conditions. In the majority of experiments there was a loss of cholesterol. Indeed we have failed to find any evidence of definite secretion or absorption save in the case of the infected gall bladder. We are led to conclude, as did Rous and McMaster (15) with regard to bile pigment, that normally there is no absorption of cholesterol.

摘要

本文报道的狗实验数据使我们得出结论,胆色素不从胆囊胆汁中被吸收。与丢失的水量相比,色素的平均损失非常小,可以忽略不计。我们的胆固醇数据不支持这种物质在正常情况下分泌到狗的胆囊胆汁中的概念。在大多数实验中,胆固醇都有损失。事实上,除了感染的胆囊外,我们没有发现任何明确分泌或吸收的证据。我们得出的结论是,正如 Rous 和 McMaster(15)关于胆色素的结论一样,通常情况下,胆固醇不会被吸收。

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本文引用的文献

1
THE CHOLESTEROL FUNCTION OF THE GALL BLADDER.
J Exp Med. 1931 Oct 31;54(5):775-87. doi: 10.1084/jem.54.5.775.
3
THE CONCENTRATING ACTIVITY OF THE GALL BLADDER.
J Exp Med. 1921 Jun 30;34(1):47-73. doi: 10.1084/jem.34.1.47.

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