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胆囊的胆固醇功能。

THE CHOLESTEROL FUNCTION OF THE GALL BLADDER.

机构信息

Department of Surgery, Washington University School of Medicine, and Barnes Hospital, St. Louis.

出版信息

J Exp Med. 1931 Oct 31;54(5):775-87. doi: 10.1084/jem.54.5.775.

DOI:10.1084/jem.54.5.775
PMID:19869958
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2132054/
Abstract

Cholesterol determinations of gall bladder and hepatic bile obtained from the same source reveal a greater concentration in the former even after the inspissating effect of the gall bladder is allowed for. This evidence together with that from other experiments indicates that the gall bladder has the power to excrete cholesterol into its lumen. There is evidence also that infection may accelerate this excretion. An hypothesis is presented to explain the precipitation of cholesterol in the bile, and the bearing of these findings on the pathogenesis of cholesterol stones is briefly discussed.

摘要

从同一来源获得的胆囊和肝胆汁的胆固醇测定显示，即使考虑到胆囊的浓缩作用，前者的浓度也更高。这一证据与其他实验的证据一起表明，胆囊具有将胆固醇排入其管腔的能力。也有证据表明感染可能加速这种排泄。提出了一个假说来解释胆汁中胆固醇的沉淀，以及这些发现对胆固醇结石发病机制的影响。

相似文献

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THE CHOLESTEROL FUNCTION OF THE GALL BLADDER.胆囊的胆固醇功能。
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引用本文的文献

1
II. BILE CHOLESTEROL : FLUCTUATIONS DUE TO DIET FACTORS, BILE SALT, LIVER INJURY AND HEMOLYSIS.二、胆汁胆固醇：饮食因素、胆汁盐、肝损伤和溶血引起的波动。
J Exp Med. 1934 Mar 31;59(4):411-25. doi: 10.1084/jem.59.4.411.
2
STUDIES ON GALL BLADDER FUNCTION : VIII. THE FATE OF BILE PIGMENT AND CHOLESTEROL IN HEPATIC BILE SUBJECTED TO GALL BLADDER ACTIVITY.胆囊功能的研究：VIII. 胆囊活动对肝胆汁中胆色素和胆固醇的影响。
J Exp Med. 1932 Jun 30;56(1):1-11. doi: 10.1084/jem.56.1.1.

本文引用的文献

1
Cholesterosis of the Gall Bladder.胆囊胆固醇沉着症
Am J Pathol. 1925 Jul;1(4):383-8.
2
STUDIES ON THE TOTAL BILE : VII. CONDITIONS INFLUENCING THE CALCIUM CONTENT OF THE BILE.总胆汁研究：VII. 影响胆汁钙含量的条件。
J Exp Med. 1924 Nov 30;40(6):797-815. doi: 10.1084/jem.40.6.797.
3
STUDIES ON THE TOTAL BILE : VI. THE INFLUENCE OF DIET UPON THE OUTPUT OF CHOLESTEROL IN THE BILE.总胆汁研究：VI. 饮食对胆汁中胆固醇排泄的影响。
J Exp Med. 1924 Jun 30;40(1):25-42. doi: 10.1084/jem.40.1.25.
4
OBSERVATIONS ON SOME CAUSES OF GALL STONE FORMATION : III. THE RELATION OF THE REACTION OF THE BILE TO EXPERIMENTAL CHOLELITHIASIS.一些胆石形成原因的观察报告：三、胆汁反应与实验性胆石症的关系。
J Exp Med. 1924 Feb 29;39(3):403-23. doi: 10.1084/jem.39.3.403.
5
A METHOD FOR THE PERMANENT STERILE DRAINAGE OF INTRAABDOMINAL DUCTS, AS APPLIED TO THE COMMON DUCT.一种用于腹腔内管道永久性无菌引流的方法，应用于胆总管。
J Exp Med. 1923 Jan 1;37(1):11-9. doi: 10.1084/jem.37.1.11.
6
PHYSIOLOGICAL CAUSES FOR THE VARIED CHARACTER OF STASIS BILE.胆汁瘀积的各种特征的生理原因。
J Exp Med. 1921 Jun 30;34(1):75-95. doi: 10.1084/jem.34.1.75.
7
The absorption of calcium from the gall-bladder.钙从胆囊的吸收。
J Physiol. 1930 Dec 4;70(4):434-40. doi: 10.1113/jphysiol.1930.sp002706.

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