Department of Pathology, Yale University School of Medicine, New Haven.
J Exp Med. 1934 Jun 30;60(1):1-7. doi: 10.1084/jem.60.1.1.
Rabbits sensitized to horse serum developed a bacteremia of 9 to 12 hours' duration when they were inoculated simultaneously with normal horse serum and a strain of Streptococcus hemolyticus, while the bacteria could only be isolated from the blood stream of non-sensitized animals within the first 3 hours after inoculation. On the other hand, when antisera are employed as the antigen for shocking the sensitized rabbits, there is a significant increase in the number of bacteria in the blood stream in contrast to the control animals, but there is no evidence of a prolongation of the bacteremia.
家兔对马血清致敏后,同时接种正常马血清和溶血性链球菌株,会导致 9 至 12 小时的菌血症,而细菌只能在接种后 3 小时内从未致敏动物的血流中分离出来。另一方面,当抗血清用作冲击致敏家兔的抗原时,与对照动物相比,血流中的细菌数量显著增加,但没有证据表明菌血症延长。