Institute of Pathology, Western Reserve University, and University Hospitals, Cleveland.
J Exp Med. 1937 Oct 31;66(5):603-16. doi: 10.1084/jem.66.5.603.
Living B. aertrycke were effective in place of aertrycke filtrate as either the preparatory or the provocative injection in the production of a positive Shwartzman reaction. When living B. aertrycke were injected subcutaneously a more severe inflammation resulted, organization was delayed, and more living organisms survived at the site of inoculation in rabbits that had received 24 hours later an intravenous injection of B. aertrycke filtrate than was the case in similarly infected rabbits that had not received a subsequent injection of bacterial filtrate. When a local state of hypersusceptibility was created by the subcutaneous injection of B. aertrycke filtrate, the subsequent (24 hours) injection of living B. aertrycke led to the development at the site of subcutaneous preparation of a hemorrhagic necrosing inflammation in which the bacteria localized.
活炭疽杆菌在制备或激发阳性施瓦茨曼反应方面与炭疽杆菌滤液同样有效。当活炭疽杆菌被皮下注射时，会导致更严重的炎症，组织延迟愈合，并且在接种部位有更多的活菌存活，这在接受 24 小时后静脉注射炭疽杆菌滤液的兔子中比在未接受后续细菌滤液注射的类似感染兔子中更为常见。当通过皮下注射炭疽杆菌滤液引起局部过敏状态时，随后（24 小时）注射活炭疽杆菌会导致在皮下准备部位发展出一种出血性坏死性炎症，细菌在其中定位。
