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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Departments of Biochemistry and Surgery of Vanderbilt University, Nashville.

J Exp Med. 1940 Aug 31;72(3):289-99. doi: 10.1084/jem.72.3.289.

In the hypertension which accompanies constriction of the renal arteries, there is no constant relationship between the height of the general systemic arterial pressure and the pressure in the renal artery distal to the point of constriction. The hypertension may persist even though the renal arterial pressure returns to or almost to the control level. 2. Studies on the renal blood flow and oxygen consumption following subtotal nephrectomy were abandoned because of inability to produce hypertension in dogs by this method. It is suggested that the mechanism of the hypertension following renal arterial constriction (dogs) and that following subtotal nephrectomy (rats) may not be the same in the two instances. 3. Studies on isolated renal cortical tissue of dogs and of rabbits following renal arterial constriction and subtotal nephrectomy showed that there is not necessarily a diminution in the capacity of the tissues of hypertensive animals to use oxygen.

在伴有肾动脉收缩的高血压中，全身动脉压的高度与狭窄后肾动脉的压力之间没有恒定的关系。即使肾动脉压恢复到或几乎恢复到对照水平，高血压仍可能持续存在。
由于不能通过这种方法在狗中产生高血压，因此放弃了关于肾切除术后肾血流和氧消耗的研究。这表明，肾动脉狭窄（狗）和肾切除术后（大鼠）引起的高血压的机制在这两种情况下可能不同。
对肾动脉狭窄和肾部分切除术后狗和兔的孤立肾皮质组织的研究表明，高血压动物组织利用氧的能力不一定会降低。

Departments of Biochemistry and Surgery of Vanderbilt University, Nashville.

J Exp Med. 1940 Aug 31;72(3):289-99. doi: 10.1084/jem.72.3.289.

In the hypertension which accompanies constriction of the renal arteries, there is no constant relationship between the height of the general systemic arterial pressure and the pressure in the renal artery distal to the point of constriction. The hypertension may persist even though the renal arterial pressure returns to or almost to the control level. 2. Studies on the renal blood flow and oxygen consumption following subtotal nephrectomy were abandoned because of inability to produce hypertension in dogs by this method. It is suggested that the mechanism of the hypertension following renal arterial constriction (dogs) and that following subtotal nephrectomy (rats) may not be the same in the two instances. 3. Studies on isolated renal cortical tissue of dogs and of rabbits following renal arterial constriction and subtotal nephrectomy showed that there is not necessarily a diminution in the capacity of the tissues of hypertensive animals to use oxygen.

在伴有肾动脉收缩的高血压中，全身动脉压的高度与狭窄后肾动脉的压力之间没有恒定的关系。即使肾动脉压恢复到或几乎恢复到对照水平，高血压仍可能持续存在。
由于不能通过这种方法在狗中产生高血压，因此放弃了关于肾切除术后肾血流和氧消耗的研究。这表明，肾动脉狭窄（狗）和肾切除术后（大鼠）引起的高血压的机制在这两种情况下可能不同。
对肾动脉狭窄和肾部分切除术后狗和兔的孤立肾皮质组织的研究表明，高血压动物组织利用氧的能力不一定会降低。