Meadows-Oliver Mikki
Yale University School of Nursing, New Haven, CT, USA.
Dermatol Nurs. 2009 Sep-Oct;21(5):281-6.
Tinea capitis is a fungal infection involving the hair shaft of the scalp. It is commonly referred to as ringworm and occurs primarily in children. Treatment with a systemic anti-fingal rather than topical treatment is required. Currently, two medications, griseofulvin (Grifulvin) and terbinafine (Lamisil Granules), are FDA-approved to treat tinea capitis. Treatment with griseofulvin is usually 6 to 8 weeks, while treatment with terbinafine requires 6 weeks. There are other medications currently not FDA-approved to treat tinea capitis that have similar cure rates and shorter durations of treatment for tinea capitis, and as a result, are being used off-label. The research-based literature related to the treatment of tinea capitis with various pharmacologic agents is reviewed.
头癣是一种涉及头皮毛发干的真菌感染。它通常被称为癣，主要发生在儿童中。需要使用全身性抗真菌药物而非局部治疗。目前，两种药物，灰黄霉素（Grifulvin）和特比萘芬（Lamisil Granules），已获美国食品药品监督管理局（FDA）批准用于治疗头癣。灰黄霉素治疗通常为6至8周，而特比萘芬治疗需要6周。目前还有其他未获FDA批准用于治疗头癣的药物，它们对头癣的治愈率相似且治疗时间更短，因此正在被超说明书使用。本文综述了与使用各种药物治疗头癣相关的基于研究的文献。
