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儿童头癣的评估与管理

The assessment and management of tinea capitis in children.

作者信息

Ali Samina, Graham Timothy A D, Forgie Sarah E D

机构信息

Division of Pediatric Emergency Medicine, Department of Pediatrics, Stollery Children's Hospital, Edmonton, Alberta, Canada.

出版信息

Pediatr Emerg Care. 2007 Sep;23(9):662-5; quiz 666-8. doi: 10.1097/PEC.0b013e31814efe06.

Abstract

Tinea capitis is an infection of the scalp and hair shaft caused by dermatophyte fungi. It is seen in all age groups, and the incidence seems to be on the rise in North America. Clinical diagnosis of tinea capitis can be challenging, as symptoms can vary from minimal pruritus with no hair loss, to severe tenderness, purulence, and permanent scarring in inflammatory kerion lesions. The diagnosis of tinea capitis must be confirmed in the laboratory by using fungal stains or obtaining cultures, since treatment may be prolonged with potential side effects. Systemic therapy is needed because topical antifungals cannot effectively penetrate the hair shaft to eradicate the infection. Oral griseofulvin remains the standard treatment agent, but terbinafine and itraconazole are also effective alternatives (although currently without Food and Drug Administration approval).

摘要

头癣是一种由皮肤癣菌引起的头皮和毛干感染。各年龄组均可发病,在北美发病率似乎呈上升趋势。头癣的临床诊断具有挑战性,因为症状差异很大,从轻微瘙痒且无脱发,到炎症性脓癣病变出现严重压痛、化脓和永久性瘢痕形成。头癣的诊断必须在实验室通过真菌染色或培养来确诊,因为治疗可能需要延长时间且有潜在副作用。由于局部抗真菌药无法有效穿透毛干以根除感染,因此需要进行全身治疗。口服灰黄霉素仍然是标准治疗药物,但特比萘芬和伊曲康唑也是有效的替代药物(尽管目前未获美国食品药品监督管理局批准)。

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