Wang Jing, Qi Haiyu, Diao Zongli, Zheng Xiaoyan, Li Xiaoli, Ma Suxia, Ji Aiping, Yin Chenghong
Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
J Parasitol. 2010 Apr;96(2):377-81. doi: 10.1645/GE-2214.1.
An outbreak of 81 cases of angiostrongyliasis cantonensis (AC) occurred in Beijing, China, during June through September 2006. Epidemiological characteristics, clinical signs and symptoms, laboratory tests, imaging, and treatment data from the 81 AC patients were collected and analyzed. All cases had a history of eating raw freshwater snails, and acquired Angiostrongylus cantonensis as a result. The incubation period ranged from 1 to 36 days. The main symptoms were fever, severe headache, neck stiffness, and skin paresthesia. A significant increase in eosinophilia occurred in the peripheral blood of 62 cases and in cerebrospinal fluid of 64 cases; 36 patients presented a linearly enhanced abnormal signal of the leptomeninges site during a cranial MRI examination, indicative of meningitis; 18 cases had a significant nodule shadow and spot flaky ground-glass shadow on chest computerized tomography. All patients were relieved of their illness with a 7-day treatment of albendazole.
2006年6月至9月期间，中国北京爆发了81例广州管圆线虫病（AC）疫情。收集并分析了81例AC患者的流行病学特征、临床症状、实验室检查、影像学检查及治疗数据。所有病例均有食用生淡水螺史，由此感染广州管圆线虫。潜伏期为1至36天。主要症状为发热、剧烈头痛、颈部僵硬及皮肤感觉异常。62例患者外周血嗜酸性粒细胞显著增多，64例患者脑脊液中嗜酸性粒细胞显著增多；36例患者头颅磁共振成像检查显示软脑膜部位呈线性强化异常信号，提示脑膜炎；18例患者胸部计算机断层扫描有明显结节影及斑片状磨玻璃影。所有患者经阿苯达唑治疗7天病情缓解。
