Eid Ali H, Itani Ziad, Al-Tannir Mohammad, Sayegh Said, Samaha Ali
Department of Biology, College of Science, United Arab Emirates University, Al-Ain, UAE.
J Cardiothorac Surg. 2009 Oct 29;4:58. doi: 10.1186/1749-8090-4-58.
Most coronary artery anomalies are congenital in origin. This study angiographically determined the prevalence of different forms of anomalous aortic origins of coronary anomalies and their anatomic variation in a selected adult Lebanese population. Correlation between these anomalies and stenotic coronary atherosclerotic disease was also investigated.
4650 coronary angiographies were analyzed for anomalous aortic origin. These anomalies were clustered in four main groups: anomalous left circumflex (LCX) coronary artery, anomalous right coronary artery, anomalous left main coronary artery and anomalous left anterior descending coronary artery.
Thirty four patients had anomalous aortic origin of coronary arteries. Of these, anomalous LCX coronary artery was the most common (19 of 34 patients). The second most common anomaly was anomalous RCA origin (9 of 34 patients.) The incidence of coronary stenosis in non-anomalous vessels was 50%. However, a significantly smaller percentage (17.46%; 6 of 34 patients) of anomalous vessels exhibited significant stenosis, reminiscent of atherosclerotic disease. Of these six vessels, five were LCX coronary artery arising from right coronary sinus or from early branch of right coronary artery. The sixth was right coronary artery arising from left coronary sinus.
The incidence of congenital coronary anomalies in Lebanon is similar to other populations where the most common is the LCX coronary artery. Isolated congenital coronary anomalies do not increase the risk of developing coronary stenosis or atherosclerosis. Angiographic detection of these anomalies is clinically important for coronary angioplasty or cardiac surgery.
大多数冠状动脉异常为先天性起源。本研究通过血管造影确定了黎巴嫩特定成年人群中不同形式的冠状动脉异常主动脉起源的患病率及其解剖变异。还研究了这些异常与狭窄性冠状动脉粥样硬化疾病之间的相关性。
对4650例冠状动脉造影进行了异常主动脉起源分析。这些异常分为四个主要组：左旋支（LCX）冠状动脉异常、右冠状动脉异常、左主冠状动脉异常和左前降支冠状动脉异常。
34例患者存在冠状动脉异常主动脉起源。其中，左旋支冠状动脉异常最为常见（34例患者中有19例）。第二常见的异常是右冠状动脉起源异常（34例患者中有9例）。非异常血管中冠状动脉狭窄的发生率为50%。然而，异常血管中出现明显狭窄的比例显著较小（17.46%；34例患者中有6例），这让人联想到动脉粥样硬化疾病。在这6支血管中，5支是起源于右冠状动脉窦或右冠状动脉早期分支的左旋支冠状动脉。第6支是起源于左冠状动脉窦的右冠状动脉。
黎巴嫩先天性冠状动脉异常的发生率与其他人群相似，最常见的是左旋支冠状动脉。孤立的先天性冠状动脉异常不会增加发生冠状动脉狭窄或动脉粥样硬化的风险。血管造影检测这些异常对冠状动脉成形术或心脏手术具有临床重要性。
