Gene therapy in perspective.

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作者信息

Weatherall D J

机构信息

Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, UK.

出版信息

Nature. 1991 Jan 24;349(6307):275-6. doi: 10.1038/349275a0.

DOI:10.1038/349275a0

PMID:1987488

Abstract

摘要

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Gene therapy in perspective.

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From molecular genetics to functional genomics and physiome.

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Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.

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相似文献

Gene therapy in perspective.

Nature. 1991 Jan 24;349(6307):275-6. doi: 10.1038/349275a0.

Targeted gene modification for gene therapy of stem cells.

Int J Cell Cloning. 1990 Mar;8(2):80-96. doi: 10.1002/stem.5530080202.

Gene transfer and the prospects for somatic gene therapy.

Hematol Oncol Clin North Am. 1988 Jun;2(2):277-87.

[Prospects for gene therapy in hematology].

Ann Biol Clin (Paris). 1999 Jan-Feb;57(1):43-50.

Gene therapy on the move.

Nature. 1991 Dec 12;354(6353):429. doi: 10.1038/354429a0.

[Ethical aspects of gene therapy].

Medicina (B Aires). 1998;58(2):229-32.

Gene transfer in the treatment of hematologic disease.

Exp Hematol. 1990 Aug;18(7):857-60.

Methods of gene transfer into hepatocytes: progress toward gene therapy.

Prog Liver Dis. 1992;10:1-24.

Human gene therapy comes of age.

Nature. 1992 Jun 11;357(6378):455-60. doi: 10.1038/357455a0.

Gene therapeutics.

Nature. 1991 Jan 24;349(6307):351-2. doi: 10.1038/349351a0.

引用本文的文献

From molecular genetics to functional genomics and physiome.

J Cell Mol Med. 2002 Oct-Dec;6(4):648-52. doi: 10.1111/j.1582-4934.2002.tb00463.x.

Study of gene delivery in a rabbit vein graft model. Improvement of the efficiency of gene transfer into vein grafts.

Jpn J Thorac Cardiovasc Surg. 1999 May;47(5):204-9. doi: 10.1007/BF03217995.

Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.

Nucleic Acids Res. 1994 Oct 25;22(21):4477-81. doi: 10.1093/nar/22.21.4477.

Gene transfer with subsequent removal of the selection gene from the host genome.

Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10558-62. doi: 10.1073/pnas.88.23.10558.

Tat- and Rev-directed antisense RNA expression inhibits and abolishes replication of human immunodeficiency virus type 1: a temporal analysis.

J Virol. 1992 Sep;66(9):5576-81. doi: 10.1128/JVI.66.9.5576-5581.1992.

Selective killing of CD4+ cells harboring a human immunodeficiency virus-inducible suicide gene prevents viral spread in an infected cell population.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):182-6. doi: 10.1073/pnas.89.1.182.