Iuldashev Sh G, Kaĭlakov A M
Probl Endokrinol (Mosk). 1977 Jul-Aug;23(4):23-6.
Pain, tactile, vibration and temperature sensitivity, and also electroexcitability of individual nerves were determined. Neuropathy incidence was almost the same among males and females. There was found no association between neuropathy and excessive weight of the patients and the type of treatment. The frequency of affection increased with the advance of age and was maximum (40.4%) in patients aged from 55 to 64 years. The frequency of neuropathy proved to depend on the duration of diabetes. Sensitivity was chiefly distributed by distal and polyneuritic type. Affection of the lower limbs occurred in all the cases. Improvement after the treatment was noted in 69.3% of patients; however, in 13.5% of cases only it was objective in character. The irritative-pain syndrome was the one which yielded to the treatment best. Analysis of the results demonstrated the treatment to be more affective in younger persons with a lesser duration and severity of diabetes. The duration of partial remission constituted from 3 to 13 months. This pointed to the necessity of prophylactic therapeutic courses.
测定了疼痛、触觉、振动和温度敏感性，以及各条神经的电兴奋性。男性和女性的神经病变发生率几乎相同。未发现神经病变与患者超重及治疗类型之间存在关联。随着年龄的增长，患病频率增加，在55至64岁的患者中最高（40.4%）。事实证明，神经病变的频率取决于糖尿病的病程。感觉障碍主要呈远端和多神经类型分布。所有病例均出现下肢受累。69.3%的患者在治疗后有改善；然而，只有13.5%的病例改善是客观的。刺激性疼痛综合征对治疗的反应最佳。结果分析表明，治疗对糖尿病病程较短、病情较轻的年轻人更有效。部分缓解的持续时间为3至13个月。这表明有必要进行预防性治疗疗程。
