Department of Internal Medicine, Cardiovascular and Metabolic Disease Centre, College of Medicine, Inje University, Seoul, Korea.
Diabet Med. 2012 Sep;29(9):e290-6. doi: 10.1111/j.1464-5491.2012.03697.x.
Diabetic peripheral neuropathy is a common complication of diabetes. This cross-sectional study investigated the prevalence and clinical characteristics of this neuropathy in patients with Type 2 diabetic mellitus treated at hospitals in Korea.
Questionnaires and medical records were used to collect data on 4000 patients with Type 2 diabetes from the diabetes clinics of 40 hospitals throughout Korea. Diabetic peripheral neuropathy was diagnosed based on a review of medical records or using the Michigan Neuropathy Screening Instrument score and monofilament test.
The prevalence of neuropathy was 33.5% (n = 1338). Multivariate analysis revealed that age, female sex, diabetes duration, lower glycated haemoglobin, treatment with oral hypoglycaemic agents or insulin, presence of retinopathy, history of cerebrovascular or peripheral arterial disease, presence of hypertension or dyslipidaemia, and history of foot ulcer were independently associated with diabetic peripheral neuropathy. Of the patients with neuropathy, 69.8% were treated for the condition and only 12.6% were aware of their neuropathy.
There was a high prevalence of peripheral neuropathy in patients with Type 2 diabetes in Korea and those patients were far more likely to have complications or co-morbidities. The proper management of diabetic peripheral neuropathy deserves attention from clinicians to ensure better management of diabetes in Korea.
糖尿病周围神经病变是糖尿病的常见并发症。本横断面研究调查了在韩国医院接受治疗的 2 型糖尿病患者中这种神经病变的患病率和临床特征。
从韩国 40 家医院的糖尿病诊所收集了 4000 名 2 型糖尿病患者的问卷和病历数据。根据病历回顾或使用密歇根神经病变筛查工具评分和单丝试验诊断糖尿病周围神经病变。
神经病变的患病率为 33.5%（n=1338）。多变量分析显示，年龄、女性、糖尿病病程、较低的糖化血红蛋白、口服降糖药或胰岛素治疗、视网膜病变、脑血管或外周动脉疾病史、高血压或血脂异常以及足部溃疡史与糖尿病周围神经病变独立相关。在患有神经病变的患者中，69.8%接受了治疗，只有 12.6%知晓自己患有神经病变。
韩国 2 型糖尿病患者周围神经病变的患病率很高，且这些患者更有可能出现并发症或合并症。适当的糖尿病周围神经病变管理值得临床医生关注，以确保韩国的糖尿病管理得到改善。
