Division of Otolaryngology, Vancouver General Hospital and University of British Columbia, British Columbia, Canada.
Laryngoscope. 2010 Jan;120(1):172-7. doi: 10.1002/lary.20692.
OBJECTIVES/HYPOTHESIS: To report two cases of primary lymphoepithelial carcinoma in the middle ear and to determine the optimal treatment for such lesions.
STUDY DESIGN/METHODS: Case reports and a systematic review of the literature.
Primary lymphoepithelial carcinoma in the middle ear is an exceptionally rare condition with only two other cases reported in the literature. There appears to be an association with Epstein-Barr virus infection and in those patients originating from the Guangdong province of China, much as is the case for similar lesions found in the nasopharynx. Piecemeal rather than en bloc excision, in combination with adjuvant radiotherapy, appears to adequately control the disease.
Primary lymphoepithelial carcinoma of the middle ear is a rare lesion, which when treated has a good prognosis.
目的/假设：报告中耳原发性淋巴上皮癌的两例病例，并确定此类病变的最佳治疗方法。
研究设计/方法：病例报告和文献系统回顾。
中耳原发性淋巴上皮癌是一种非常罕见的疾病，文献中仅报告了另外两例。似乎与 Epstein-Barr 病毒感染有关，而且在中国广东省的患者中，与类似的鼻咽部病变情况相同。分片切除而非整块切除，结合辅助放疗，似乎可以充分控制疾病。
中耳原发性淋巴上皮癌是一种罕见病变，经治疗后预后良好。
