Merz H, Marnitz S, Erbersdobler A, Goektas O
Klinik für Hals-, Nasen-, Ohrenheilkunde, Charité Campus Mitte, Berlin, Germany.
Case Rep Oncol. 2010 Mar 24;3(1):77-82. doi: 10.1159/000302139.
Lymphoepithelial tumors are the most common carcinomas of the nasopharynx. The non-differentiated tumor, also called Schmincke's tumor, is more prevalent in the African and Chinese population. The incidence of the tumor according to age peaks between 20 and 30 years of age, and after 60 years of age. The tumor is rarely located outside of the nasopharynx. Case Report: This report is about a 73-year-old female patient diagnosed with a tumor of the base of the tongue. The histological result shows a low-grade carcinoma of the squamous epithelium, a lymphoepithelial carcinoma. CONCLUSION: Despite the tumor's rare manifestation outside the nasopharynx, one must also consider the non-differentiated carcinoma of lymphoepithelial matrix. Especially due to the well-known early tumor spreading, cervical lymph node swelling on both sides can be recognized as a possible early symptom. First-line therapy consists of primary radiation of the tumor's primary region and its lymphoid draining channels. Concomitant chemotherapy can be applied. In case of cervical tumor spreading, a neck dissection reduces the risk of local recurrence.
淋巴上皮瘤是鼻咽癌最常见的类型。未分化肿瘤,也称为施密克瘤,在非洲人和中国人中更为普遍。该肿瘤的发病率在20至30岁以及60岁以后达到高峰。该肿瘤很少发生在鼻咽部以外。病例报告:本报告讲述的是一名73岁女性患者,被诊断为舌根肿瘤。组织学结果显示为低级别鳞状上皮癌,即淋巴上皮癌。结论:尽管该肿瘤在鼻咽部以外很少见,但也必须考虑淋巴上皮基质的未分化癌。特别是由于众所周知的肿瘤早期扩散,双侧颈部淋巴结肿大可被视为可能的早期症状。一线治疗包括对肿瘤原发区域及其淋巴引流通道进行原发放疗。可同时进行化疗。如果出现颈部肿瘤扩散,颈部清扫术可降低局部复发风险。