带状疱疹患者中的未诊断糖尿病
Undiagnosed diabetes mellitus in patients with Herpes Zoster.
作者信息
Nassaji-Zavareh Mohammad, Taheri Ramin, Ghorbani Raheb, Aminian Maryam
机构信息
Department of Infectious Diseases, Semnan University of Medical Sciences, Semnan, Iran.
出版信息
Indian J Dermatol. 2008;53(3):119-21. doi: 10.4103/0019-5154.43211.
BACKGROUND
Herpes Zoster (HZ) is reactivation of latent varicella-zoster virus that involves dermatomes. Aging and immunosupressed states are among the main risk factors. Some investigations showed that HZ is more common in diabetic patients than in normal population.
AIM
To determine whether undiagnosed DM is more common in patients with HZ than in those without it.
MATERIALS AND METHODS
In this study 103 patients with HZ (cases) and 142 as control participated. They had no history of DM. Both groups were matched according to age, gender and family history of DM. Fasting plasma glucose was checked for all participants. DM was defined when the fasting plasma glucose was equal or more 126 mg/dl.
RESULTS
35.9% of patients with HZ and 19.7% of the control group had DM. There was significant association between HZ and undiagnosed DM (OR = 2.28, 95% CI: 1.28-4.06).
CONCLUSION
Our findings indicate that the prevalence of undiagnosed DM is more common in HZ patients and supports the policy to investigate patients with HZ for the presence of undiagnosed DM.
背景
带状疱疹（HZ）是潜伏的水痘-带状疱疹病毒的再激活，累及皮节。衰老和免疫抑制状态是主要危险因素。一些调查显示，糖尿病患者中HZ比正常人群更常见。
目的
确定未诊断的糖尿病在HZ患者中是否比非HZ患者更常见。
材料与方法
本研究纳入103例HZ患者（病例组）和142例作为对照组。他们均无糖尿病病史。两组根据年龄、性别和糖尿病家族史进行匹配。对所有参与者进行空腹血糖检查。空腹血糖等于或高于126mg/dl时定义为糖尿病。
结果
HZ患者中35.9%患有糖尿病，对照组中19.7%患有糖尿病。HZ与未诊断的糖尿病之间存在显著关联（OR = 2.28，95%CI：1.28 - 4.06）。
结论
我们的研究结果表明，未诊断的糖尿病在HZ患者中更常见，并支持对HZ患者进行未诊断糖尿病筛查的策略。
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