Guidetti D, Gabbi E, Motti L, Ferrarini G
Divisione Neurologica, Arcispedale Santa Maria Nuova, Reggio Emilia.
Ital J Neurol Sci. 1990 Dec;11(6):559-65. doi: 10.1007/BF02337438.
We report 31 cases of herpes zoster (HZ) with neurological complications: 14 with cranial nerve deficits, 1 with cranial nerve deficit associated with segmental motor disorder, 3 with segmental motor deficits, 2 with meningoencephalitis, 2 with meningoencephalitis associated with cranial neuropathy or myelitis, 2 with meningitis, 2 with hemiplegia contralateral to the ophthalmic HZ. 1 with hemiplegia and motor deficit and finally 1 with hemiplegia and a cranial neuropathy. Smoking was the putative risk factor in 53% of our patients together with diabetes, which has already been mentioned in the literature. We frequently observed more than one complication in succession (19.3%) that could not easily be related to the cutaneous distribution. Acyclovir had no demonstrable positive effects on neurological complication in our patients.
我们报告了31例伴有神经并发症的带状疱疹(HZ):14例有颅神经缺损,1例有颅神经缺损合并节段性运动障碍,3例有节段性运动缺损,2例有脑膜脑炎,2例有脑膜脑炎合并颅神经病变或脊髓炎,2例有脑膜炎,2例有与眼部HZ对侧的偏瘫。1例有偏瘫和运动缺损,最后1例有偏瘫和颅神经病变。在我们53%的患者中,吸烟被认为是危险因素,糖尿病也是危险因素,这在文献中已有提及。我们经常连续观察到不止一种并发症(19.3%),这些并发症不易与皮肤分布相关联。阿昔洛韦对我们患者的神经并发症没有明显的积极作用。