脓毒症中的微循环功能障碍。
Microcirculatory dysfunction in sepsis.
机构信息
Department of Surgery, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA.
出版信息
Crit Care Clin. 2009 Oct;25(4):721-31, viii. doi: 10.1016/j.ccc.2009.06.002.
This article discusses the role of microcirculatory dysfunction in the pathophysiology of sepsis, reviewing the role of the endothelium in modulating microcirculatory flow, discussing the function of nitric oxide in mediating microcirculatory blood flow, and outlining means of evaluating microcirculatory function in septic patients. Finally, potential novel therapies and challenges in treating microcirculatory dysfunction in septic patients are discussed.
本文讨论了微循环功能障碍在脓毒症病理生理学中的作用，回顾了内皮细胞在调节微循环血流中的作用，讨论了一氧化氮在介导微循环血流中的功能，并概述了评估脓毒症患者微循环功能的方法。最后，讨论了治疗脓毒症患者微循环功能障碍的潜在新疗法和挑战。
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