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[采用和不采用呼气末正压的肺部物理治疗对慢性支气管炎的长期治疗]

[Long-term treatment of chronic bronchitis with pulmonary physiotherapy with and without positive expiratory pressure].

作者信息

Christensen E F, Nedergaard T, Dahl R

机构信息

Lungeklinikken og lungemedicinsk afdeling, Arhus Kommunehospital.

出版信息

Ugeskr Laeger. 1991 Jan 7;153(2):113-6.

PMID:1989365
Abstract

In a prospective, randomized, controlled study, treatment of chronic bronchitis with self-administered chest physiotherapy alone (control) or with positive expiratory pressure (PEP) by mask was studied. Forty-three patients completed the study (n = 20 PEP, and n = 23 control). After instruction, the treatments were self-administered twice daily for 12 months (34 patients) and five months (9 patients). The patients completed a diary concerning symptoms twice weekly. An acute exacerbation (AE) was defined as the appearance of mucopurulent or purulent sputum and increasing cough and one or more of the following symptoms: temperature greater than or equal to 38 degrees C, general malaise, increased dyspnea, increased mucus production, increased thickness of mucus or increased difficulty in expectoration. The number of AE were calculated from the diaries. The incidence of AE was significantly lower in the PEP group (p less than 0.0005). In the PEP group, three patients had a total of six AE, compared to 12 patients with 28 AE in the control group. The PEP group also used less antibiotics (p less than 0.005). Treatment with a simple PEP device can reduce morbidity in patients with chronic bronchitis.

摘要

在一项前瞻性、随机、对照研究中,研究了单独采用自我实施的胸部物理治疗(对照组)或通过面罩进行呼气末正压(PEP)治疗慢性支气管炎的效果。43例患者完成了研究(PEP组20例,对照组23例)。经过指导后,治疗由患者每天自行进行2次,持续12个月(34例患者)和5个月(9例患者)。患者每周两次记录症状日记。急性加重(AE)定义为出现黏液脓性或脓性痰液、咳嗽加重以及以下一种或多种症状:体温大于或等于38摄氏度、全身不适、呼吸困难加重、黏液分泌增加、黏液变稠或咳痰困难增加。AE的数量根据日记计算得出。PEP组的AE发生率显著更低(p<0.0005)。PEP组有3例患者共发生6次AE,而对照组有12例患者发生28次AE。PEP组使用的抗生素也更少(p<0.005)。使用简单的PEP装置进行治疗可降低慢性支气管炎患者的发病率。

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