Reynolds R D, Greenberg B R, Hill R, Lucas R N, Shirley J H
West J Med. 1977 Sep;127(3):190-4.
Analysis was carried out according to stage and tissue type of 392 consecutive cases of lung cancer diagnosed at David Grant Medical Center between 1960 and 1974. Biphasic survival curves were described with a variable primary phase and a constant (1.1 percent per month) secondary phase. Survival was found to correlate both to histology and stage. The best survival was found in stage I bronchoalveolar carcinoma. Even in the more favorable categories a leveling off of survival was not found. This study strongly suggests that surgical treatment of lung cancer, while beneficial, cannot expect to be considered as a curative procedure in more than 10 percent of cases. Radiotherapy did not prolong survival.
对1960年至1974年间在大卫·格兰特医疗中心确诊的392例连续肺癌病例，根据分期和组织类型进行了分析。描述了双相生存曲线，其具有可变的初始阶段和恒定的（每月1.1%）第二阶段。发现生存率与组织学和分期均相关。I期细支气管肺泡癌的生存率最佳。即使在更有利的类别中，也未发现生存率趋于平稳。这项研究强烈表明，肺癌的手术治疗虽然有益，但在超过10%的病例中不能被视为一种治愈性方法。放射治疗并未延长生存期。
