Leroith Tanya, Binder Ellen M, Graham A Heather, Duncan Robert B
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA.
J Vet Diagn Invest. 2009 Nov;21(6):918-20. doi: 10.1177/104063870902100630.
A 6-month-old, intact, male Weimaraner dog presented to the veterinary teaching hospital for bilateral mucopurulent ocular and nasal discharge that began at approximately 10 weeks of age. A computed tomography scan showed an expansile soft-tissue mass involving both frontal sinuses, the ethmoid regions, and nasal cavities with lysis of the maxillary turbinates and hyperostosis of the walls of the frontal sinus. The dog was euthanized after complications during a trephination and biopsy procedure. At necropsy, a large, tan, papillary, gelatinous mass filled the entire nasal cavity and frontal sinus. The mass was composed of large fronds of loose fibrovascular stroma covered by a single layer of pseudostratified, columnar, ciliated epithelium and intermixed goblet cells. The cells occasionally formed glandular structures that were continuous with the surface epithelium. The mass was diagnosed as a respiratory epithelial adenomatoid hamartoma based on the morphologic appearance.
一只6个月大、未绝育的雄性魏玛犬因双侧黏液脓性眼鼻分泌物就诊于兽医教学医院，该症状始于约10周龄。计算机断层扫描显示一个膨胀性软组织肿块，累及双侧额窦、筛窦区域和鼻腔，伴有上颌鼻甲溶解和额窦壁骨质增生。这只狗在环钻活检过程中出现并发症后实施了安乐死。尸检时，一个大的、黄褐色、乳头状、凝胶状肿块充满整个鼻腔和额窦。该肿块由松散的纤维血管基质的大叶片组成，表面覆盖单层假复层柱状纤毛上皮，并夹杂杯状细胞。这些细胞偶尔形成与表面上皮连续的腺结构。根据形态学表现，该肿块被诊断为呼吸道上皮腺瘤样错构瘤。
