Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Spinal Cord. 2010 Jun;48(6):492-7. doi: 10.1038/sc.2009.158. Epub 2009 Nov 10.
Investigation of burden of traumatic spinal cord injury (SCI) using disease modeling.
The present paper is intended to estimate the SCI burden for the year 2008.
Tehran, capital of Iran.
Epidemiological data needed to calculate Disability-Adjusted Life-Years (DALYs) for SCI, was estimated according to prevalence, duration and relative risk of mortality using DISMOD software. For DALY calculation, the years of life lost because of premature mortality (YLL) was added to the number of years lost because of disability (YLD). To calculate DALYs for SCI, first year DALY calculated separately and for the next years, the DALY was assessed for six different clinical presentations of traumatic SCI including quadriplegia, quadriparesis, paraplegia, paraparesis, hemiplegia and hemiparesis.
In first year following SCI, the DALY was 3772 years, which has 0.5 DALY per 1000 people and YLL/DALY was 89.3%. Following the first year, the DALY was 435 for quadriplegia, 163 for quadriparesis, 868 for paraplegia, 164 for paraparesis, 26 for hemiplegia and 14 for hemiparesis. The total YLL for traumatic SCI was 4077 years and total YLD was 1364 years (total YLL/DALY was 74.9%) and total DALY was 5441 years, (M/F=2.0), which has 0.7 DALY per 1000 people in Tehran in 2008.
This study showed a high burden for SCI. Identifying the risk factors of SCI, and performing cost-effective preventive interventions for reducing burden of SCI is recommended.
使用疾病建模研究创伤性脊髓损伤(SCI)的负担。
本研究旨在估计 2008 年 SCI 的负担。
伊朗首都德黑兰。
根据患病率、持续时间和相对死亡率,使用 DISMOD 软件估算计算 SCI 残疾调整生命年(DALY)所需的流行病学数据。为了计算 DALY,将因过早死亡而损失的生命年(YLL)与因残疾而损失的生命年(YLD)相加。为了计算 SCI 的 DALY,首先单独计算第一年的 DALY,对于下一年,评估创伤性 SCI 的六种不同临床表现的 DALY,包括四肢瘫痪、四肢瘫痪、截瘫、截瘫、偏瘫和偏瘫。
在 SCI 后的第一年,DALY 为 3772 年,每 1000 人中有 0.5 DALY,YLL/DALY 为 89.3%。在第一年之后,四肢瘫痪的 DALY 为 435 年,四肢瘫痪为 163 年,截瘫为 868 年,截瘫为 164 年,偏瘫为 26 年,偏瘫为 14 年。创伤性 SCI 的总 YLL 为 4077 年,总 YLD 为 1364 年(总 YLL/DALY 为 74.9%),总 DALY 为 5441 年(M/F=2.0),2008 年德黑兰每 1000 人中有 0.7 DALY。
本研究显示 SCI 负担沉重。建议确定 SCI 的危险因素,并进行具有成本效益的预防干预,以减轻 SCI 的负担。