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母亲在怀孕期间使用泼尼松导致低血糖性癫痫发作和新生儿急性肾上腺功能不全：病例报告。

Hypoglycaemic seizure and neonatal acute adrenal insufficiency after maternal exposure to prednisone during pregnancy: a case report.

机构信息

Department of Clinical Pharmacology and Regional Center of Pharmacovigilance, CHU de Poitiers, Poitiers, France.

出版信息

Eur J Pediatr. 2010 Jun;169(6):763-5. doi: 10.1007/s00431-009-1095-9. Epub 2009 Nov 10.

DOI:10.1007/s00431-009-1095-9
PMID:19902248
Abstract

Neonatal acute adrenal insufficiency (AAI) is a rare but severe condition. We report a case of AAI following maternal exposure to moderate doses of corticosteroids during pregnancy. The neonate, born at term, presented with hypoglycaemia complicated by seizures. The AAI was confirmed by endocrine tests and after exclusion of differential diagnoses. Early diagnosis and treatment led to full recovery.

摘要

新生儿急性肾上腺功能不全（AAI）是一种罕见但严重的疾病。我们报告了一例母体在妊娠期间接受中等剂量皮质类固醇暴露后发生的 AAI。该新生儿足月出生，表现为低血糖伴发癫痫。内分泌检查证实了 AAI 的诊断，并排除了鉴别诊断。早期诊断和治疗导致完全康复。

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本文引用的文献

1
Maternal corticosteroid use and hypospadias.母体使用皮质类固醇与尿道下裂
J Pediatr. 2009 Jul;155(1):39-44, 44.e1. doi: 10.1016/j.jpeds.2009.01.039. Epub 2009 Apr 24.
2
High-dose methylprednisolone in a pregnant woman with Crohn's disease and adrenal suppression in her newborn.一名患有克罗恩病的孕妇使用大剂量甲基强的松龙后其新生儿出现肾上腺抑制
Neonatology. 2008;94(4):306-9. doi: 10.1159/000151652. Epub 2008 Sep 11.
3
Multiple courses of antenatal steroids.多疗程产前使用类固醇激素。
妊娠期炎症性肠病的治疗见解。
Therap Adv Gastroenterol. 2019 May 27;12:1756284819852231. doi: 10.1177/1756284819852231. eCollection 2019.
4
Maternal use of prednisolone is unlikely to be associated with neonatal adrenal suppression-a single-center study of 16 cases.母亲使用泼尼松龙不太可能与新生儿肾上腺抑制相关——一项对16例病例的单中心研究。
Eur J Pediatr. 2017 Aug;176(8):1131-1136. doi: 10.1007/s00431-017-2949-1. Epub 2017 Jul 10.
5
[Dermatological topical and systemic therapy during pregnancy].[孕期的皮肤科局部和全身治疗]
Hautarzt. 2017 Feb;68(2):127-135. doi: 10.1007/s00105-016-3921-0.
6
Fetal adrenal suppression due to maternal corticosteroid use: case report.母亲使用皮质类固醇导致胎儿肾上腺抑制：病例报告。
J Clin Res Pediatr Endocrinol. 2011;3(3):160-2. doi: 10.4274/jcrpe.v3i3.31.
Indian J Pediatr. 2007 May;74(5):463-9. doi: 10.1007/s12098-007-0079-x.
4
[Fluticasone propionate in children and infants with asthma].[丙酸氟替卡松用于儿童和婴幼儿哮喘]
Arch Pediatr. 2007 Apr;14(4):376-87. doi: 10.1016/j.arcped.2006.11.026. Epub 2007 Feb 7.
5
[Acute adrenal insufficiency in the newborn].
Arch Pediatr. 2006 Oct;13(10):1358-63. doi: 10.1016/j.arcped.2006.07.016. Epub 2006 Sep 7.
6
Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.产前使用糖皮质激素促进早产风险女性胎儿肺成熟。
Cochrane Database Syst Rev. 2006 Jul 19(3):CD004454. doi: 10.1002/14651858.CD004454.pub2.
7
Adrenocortical reserve of neonates born of long-term, steroid-treated mothers.
Eur J Pediatr. 1984 Sep;142(4):279-80. doi: 10.1007/BF00540252.
8
Adrenocorticosteroid therapy in pregnancy.孕期的肾上腺皮质类固醇治疗。
Am J Obstet Gynecol. 1966 Dec 1;96(7):985-9. doi: 10.1016/0002-9378(66)90444-3.
9
Corticosteroids and pregnancy.皮质类固醇与妊娠。
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10
[Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France].[药物意外或毒性作用的归因。法国所用方法的更新]
Therapie. 1985 Mar-Apr;40(2):111-8.