母亲在怀孕期间使用泼尼松导致低血糖性癫痫发作和新生儿急性肾上腺功能不全：病例报告。
Hypoglycaemic seizure and neonatal acute adrenal insufficiency after maternal exposure to prednisone during pregnancy: a case report.
机构信息
Department of Clinical Pharmacology and Regional Center of Pharmacovigilance, CHU de Poitiers, Poitiers, France.
出版信息
Eur J Pediatr. 2010 Jun;169(6):763-5. doi: 10.1007/s00431-009-1095-9. Epub 2009 Nov 10.
PMID:19902248
Abstract
Neonatal acute adrenal insufficiency (AAI) is a rare but severe condition. We report a case of AAI following maternal exposure to moderate doses of corticosteroids during pregnancy. The neonate, born at term, presented with hypoglycaemia complicated by seizures. The AAI was confirmed by endocrine tests and after exclusion of differential diagnoses. Early diagnosis and treatment led to full recovery.
摘要
新生儿急性肾上腺功能不全（AAI）是一种罕见但严重的疾病。我们报告了一例母体在妊娠期间接受中等剂量皮质类固醇暴露后发生的 AAI。该新生儿足月出生，表现为低血糖伴发癫痫。内分泌检查证实了 AAI 的诊断，并排除了鉴别诊断。早期诊断和治疗导致完全康复。
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