Celiac disease.

Celiac disease is a malabsorptive disorder resulting from intolerance to gluten and leads to systemic problems due to nutritional deficiencies. Enhanced diagnostic ability through serology has led to the understanding that it is more common than previously thought and often presents in atypical and subclinical forms. Clinicians must recognize the subtle presentations that may represent celiac disease, as well as at-risk populations, so that appropriate measures can be taken to diagnose and treat the disorder.