FER酪氨酸激酶的细胞核与细胞质定位
Nuclear and cytoplasmic location of the FER tyrosine kinase.
作者信息
Hao Q L, Ferris D K, White G, Heisterkamp N, Groffen J
机构信息
Department of Pathology, Childrens Hospital, Los Angeles 90027.
出版信息
Mol Cell Biol. 1991 Feb;11(2):1180-3. doi: 10.1128/mcb.11.2.1180-1183.1991.
Abstract
The location of the FER protein within the cell was investigated by using subcellular fractionation and immunofluorescence. FER was found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes.
摘要
通过亚细胞分级分离和免疫荧光技术研究了FER蛋白在细胞内的定位。FER存在于细胞质和细胞核中，在细胞核中它与染色质部分相关联。其广泛的表达和亚细胞定位表明它可能参与关键的调节过程。
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