Brillowska-Dabrowska Anna, Bergmann Olav, Jensen Irene Moeller, Jarløv Jens Otto, Arendrup Maiken C
Unit of Mycology and Parasitology, Statens Serum Institute, Copenhagen, Denmark.
Scand J Infect Dis. 2010;42(2):109-13. doi: 10.3109/00365540903348336.
We investigated the relationship between colonizing and invasive isolates from patients with candidaemia. Molecular typing was performed using random amplification of polymorphic DNA (RAPD) and multilocus sequence typing (MLST). We found MLST to be sufficient for typing Candida isolates, and that surveillance cultures are helpful in predicting concomitant invasive isolates, but not necessarily the pathogen involved in subsequent episodes.
我们研究了念珠菌血症患者中定殖菌株与侵袭性分离株之间的关系。使用随机扩增多态性DNA（RAPD）和多位点序列分型（MLST）进行分子分型。我们发现MLST足以对念珠菌分离株进行分型，并且监测培养有助于预测伴随的侵袭性分离株，但不一定能预测后续感染事件中涉及的病原体。
