Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611-3008, USA.
Curr Opin Urol. 2010 Jan;20(1):7-12. doi: 10.1097/MOU.0b013e3283336f3f.
The epidemic of obesity and concomitant metabolic syndrome is well documented. New evidence points to a connection between the components of metabolic syndrome and benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).
Multiple studies have demonstrated a strong independent association between the components of metabolic syndrome and BPH/LUTS. Furthermore, modifiable risk factors, such as increased physical activity, appear to decrease the risk of BPH/LUTS.
Emerging data points to a strong relationship between metabolic syndrome and BPH/LUTS, indicating a common cause. Further exploration of this relationship may result in a new understanding of the pathophysiology, treatment, and prevention of these disorders.
肥胖症和随之而来的代谢综合征的流行已得到充分证实。新的证据表明,代谢综合征的组成部分与良性前列腺增生(BPH)和下尿路症状(LUTS)之间存在联系。
多项研究表明,代谢综合征的组成部分与 BPH/LUTS 之间存在强烈的独立关联。此外,可改变的危险因素,如增加身体活动,似乎可以降低 BPH/LUTS 的风险。
新出现的数据表明代谢综合征与 BPH/LUTS 之间存在很强的关系,表明存在共同的病因。进一步探索这种关系可能会导致对这些疾病的病理生理学、治疗和预防有新的认识。