Ankara Numune Education and Research Hospital, 1st Urology Clinic, Ulku Mah., Ankara, 06100, Turkey.
Aging Male. 2011 Mar;14(1):48-52. doi: 10.3109/13685538.2010.529197. Epub 2010 Nov 19.
The aim of this study was to investigate the relationship among metabolic syndrome (MetS), erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH).
Our study included 106 patients with BPH, 33 (31.1%) of whom had MetS. Blood pressures, waist circumferences, serum levels of fasting blood glucose, high density lipoprotein and triglyceride of patients were recorded. Erectile functions of the patients were evaluated by International Index of Erectile Function (IIEF). Patients were divided into two groups according to IIEF scores, namely 'mild/no ED' and 'moderate/severe ED'. IIEF scores of ED groups were between 17 and 30 and 6-16 in turn. LUTS severities were assessed by International Prostate Symptom Score (IPSS) and classified as mild (IPSS 0-7), moderate (IPSS 8-19) and severe (IPSS 20-35).
There was a significant difference between ED groups concerning MetS presence (p=0.032). MetS presence was not found to be associated with the severity of LUTS (p=0.144). There was no correlation between ED groups regarding LUTS severity (p=0.303).
Results of the present study showed a correlation between MetS presence and ED. In the light of our results, MetS seems to play an important role in the etiopathogenesis of ED in patients with BPH.
本研究旨在探讨良性前列腺增生（BPH）患者中代谢综合征（MetS）、勃起功能障碍（ED）和下尿路症状（LUTS）之间的关系。
本研究纳入 106 例 BPH 患者，其中 33 例（31.1%）患有 MetS。记录患者的血压、腰围、空腹血糖、高密度脂蛋白和甘油三酯血清水平。采用国际勃起功能指数（IIEF）评估患者的勃起功能。根据 IIEF 评分将患者分为两组，即“轻度/无 ED”和“中度/重度 ED”。ED 组的 IIEF 评分分别为 17-30 分和 6-16 分。采用国际前列腺症状评分（IPSS）评估 LUTS 严重程度，并分为轻度（IPSS 0-7）、中度（IPSS 8-19）和重度（IPSS 20-35）。
ED 组之间存在 MetS 存在的显著差异（p=0.032）。MetS 存在与 LUTS 严重程度无关（p=0.144）。ED 组之间的 LUTS 严重程度无相关性（p=0.303）。
本研究结果表明 MetS 存在与 ED 之间存在相关性。根据我们的结果，MetS 似乎在 BPH 患者 ED 的发病机制中起重要作用。
