The Institute of Scientific and Industrial Research (ISIR), Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan.
Chem Commun (Camb). 2009 Dec 7(45):6949-51. doi: 10.1039/b914770e. Epub 2009 Oct 16.
We report protein surface binding of dendritic ruthenium(ii) tris(bipyiridine) complexes to alpha-chymotrypsin, resulting in a 1 : 1 and 1 : 2 protein complex formation as well as inhibition of the enzyme activity.
我们报道了树枝状钌(II)三(联吡啶)配合物与糜蛋白酶的蛋白质表面结合,导致 1:1 和 1:2 的蛋白质复合物形成以及酶活性的抑制。