• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

视交叉上核中神经元的自由运行周期:其对神经元耦合强度分布的依赖性。

Free-running period of neurons in the suprachiasmatic nucleus: Its dependence on the distribution of neuronal coupling strengths.

作者信息

Gu Changgui, Wang Jianxiong, Liu Zonghua

机构信息

Department of Physics, East China Normal University, Institute of Theoretical Physics, Shanghai 200062, China.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Sep;80(3 Pt 1):030904. doi: 10.1103/PhysRevE.80.030904. Epub 2009 Sep 30.

DOI:10.1103/PhysRevE.80.030904
PMID:19905055
Abstract

The suprachiasmatic nucleus (SCN) pacemaker shows a free-running period ranging from 20 to 28 h for different species, which was usually explained from the angle of coupling strength. Based on the assumption of nonidentical coupling strengths in SCN, we find an alternative mechanism that the diversity of free-running period can be also caused by the distribution of coupling strengths. The free-running period is proportional to the average coupling strength and inverse proportional to the dispersion of couplings. Moreover, we present an analytic phase model to confirm our finding, which shows a solid foundation of our finding and opens a window to study the collective behaviors of SCN oscillators.

摘要

视交叉上核(SCN)起搏器在不同物种中的自由运转周期为20至28小时,这通常是从耦合强度的角度来解释的。基于SCN中耦合强度不同的假设,我们发现了另一种机制,即自由运转周期的多样性也可能由耦合强度的分布引起。自由运转周期与平均耦合强度成正比,与耦合的离散度成反比。此外,我们提出了一个解析相位模型来证实我们的发现,这为我们的发现奠定了坚实的基础,并为研究SCN振荡器的集体行为打开了一扇窗口。

相似文献

1
Free-running period of neurons in the suprachiasmatic nucleus: Its dependence on the distribution of neuronal coupling strengths.视交叉上核中神经元的自由运行周期:其对神经元耦合强度分布的依赖性。
Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Sep;80(3 Pt 1):030904. doi: 10.1103/PhysRevE.80.030904. Epub 2009 Sep 30.
2
Impact of dispersed coupling strength on the free running periods of circadian rhythms.分散耦合强度对昼夜节律自由运行周期的影响。
Phys Rev E. 2016 Mar;93(3):032414. doi: 10.1103/PhysRevE.93.032414. Epub 2016 Mar 23.
3
Entrainment range of nonidentical circadian oscillators by a light-dark cycle.明暗周期对不同昼夜节律振荡器的同步范围
Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Aug;88(2):022702. doi: 10.1103/PhysRevE.88.022702. Epub 2013 Aug 2.
4
The proportion of light-responsive neurons determines the limit cycle properties of the suprachiasmatic nucleus.光响应神经元的比例决定了视交叉上核的极限环特性。
J Biol Rhythms. 2014 Feb;29(1):16-27. doi: 10.1177/0748730413516752.
5
Mechanism of phase splitting in two coupled groups of suprachiasmatic-nucleus neurons.两组耦合的视交叉上核神经元中的相分离机制。
Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Apr;83(4 Pt 2):046224. doi: 10.1103/PhysRevE.83.046224. Epub 2011 Apr 27.
6
Adaptive coupling between neurons widens the entrainment range of the suprachiasmatic nucleus.神经元的自适应耦合拓宽了视交叉上核的节律同步范围。
Phys Rev E. 2024 Sep;110(3-1):034212. doi: 10.1103/PhysRevE.110.034212.
7
Phase differences between SCN neurons and their role in photoperiodic encoding; a simulation of ensemble patterns using recorded single unit electrical activity patterns.视交叉上核神经元之间的相位差异及其在光周期编码中的作用;使用记录的单个单元电活动模式对集合模式进行模拟。
J Physiol Paris. 2006 Nov-Dec;100(5-6):261-70. doi: 10.1016/j.jphysparis.2007.05.005. Epub 2007 Jun 8.
8
Clustering predicted by an electrophysiological model of the suprachiasmatic nucleus.视交叉上核电生理模型预测的聚类
J Biol Rhythms. 2009 Aug;24(4):322-33. doi: 10.1177/0748730409337601.
9
Regional circadian period difference in the suprachiasmatic nucleus of the mammalian circadian center.哺乳动物昼夜节律中枢视交叉上核的区域性昼夜周期差异。
Eur J Neurosci. 2013 Sep;38(6):2832-41. doi: 10.1111/ejn.12308. Epub 2013 Jul 22.
10
Circadian entrainment aftereffects in suprachiasmatic nuclei and peripheral tissues in vitro.体外视交叉上核和外周组织中的昼夜节律夹带后效应
Brain Res. 2008 Sep 4;1228:127-34. doi: 10.1016/j.brainres.2008.05.091. Epub 2008 Jun 14.

引用本文的文献

1
Network Structure of the Master Clock Is Important for Its Primary Function.主时钟的网络结构对其主要功能至关重要。
Front Physiol. 2021 Aug 16;12:678391. doi: 10.3389/fphys.2021.678391. eCollection 2021.
2
Astrocytic Modulation of Neuronal Activity in the Suprachiasmatic Nucleus: Insights from Mathematical Modeling.星形胶质细胞对视交叉上核神经元活动的调节:数学建模的见解。
J Biol Rhythms. 2020 Jun;35(3):287-301. doi: 10.1177/0748730420913672. Epub 2020 Apr 14.
3
The effects of non-self-sustained oscillators on the en-trainment ability of the suprachiasmatic nucleus.
非自维持振荡器对视交叉上核的驯化能力的影响。
Sci Rep. 2016 Nov 21;6:37661. doi: 10.1038/srep37661.
4
The synchronization of neuronal oscillators determined by the directed network structure of the suprachiasmatic nucleus under different photoperiods.不同光周期下视交叉上核有向网络结构决定的神经元振荡器同步。
Sci Rep. 2016 Jun 30;6:28878. doi: 10.1038/srep28878.
5
Heterogeneity induces rhythms of weakly coupled circadian neurons.异质性诱导弱耦合昼夜节律神经元的节律。
Sci Rep. 2016 Feb 22;6:21412. doi: 10.1038/srep21412.
6
Noise Induces Oscillation and Synchronization of the Circadian Neurons.噪声诱导昼夜节律神经元的振荡和同步。
PLoS One. 2015 Dec 21;10(12):e0145360. doi: 10.1371/journal.pone.0145360. eCollection 2015.
7
Photic desynchronization of two subgroups of circadian oscillators in a network model of the suprachiasmatic nucleus with dispersed coupling strengths.具有离散耦合强度的视交叉上核网络模型中两个 circadian 振荡器亚群的光耦合失同步。
PLoS One. 2012;7(5):e36900. doi: 10.1371/journal.pone.0036900. Epub 2012 May 16.