Norwegian School of Sport Sciences, Department of Sports Medicine, Oslo, Norway.
BJOG. 2009 Dec;116(13):1706-14. doi: 10.1111/j.1471-0528.2009.02379.x.
To investigate the risk factors for pelvic organ prolapse (POP), including physical activity, clinically measured joint mobility and pelvic floor muscle (PFM) function.
One-to-one age- and parity-matched case-control study.
Akershus university hospital and one outpatient physiotherapy clinic in Norway.
Forty-nine women with POP (POP quantification, stage>or=II) and 49 controls (stages 0 and I) were recruited from community gynaecologists and advertisements in newspapers.
Validated questionnaires, interview and clinical examination, including Beighton's scoring system (joint hypermobility) and vaginal pressure transducer measurements (PFM function), were used. Univariate and multivariate conditional logistic regression analyses for one-to-one matched case-control studies were used, and odds ratios with 95% CIs are reported.
Pelvic floor muscle function (strength, endurance and resting pressure), socioeconomic status, body mass index, heavy occupational work, physical activity, family history, obstetric factors and markers of connective tissue weakness (striae, varicose veins, bruising, diastasis recti abdominis, joint hypermobility).
No significant differences were found between groups with regard to postmenopausal status, current smoking, current low-intensity exercise, type of birth (caesarean, forceps, vacuum), birth weight, presence of striae, diastasis recti abdominis and joint hypermobility. Body mass index (OR 5.0; 95% CI 1.1-23.0), socioeconomic status (OR 10.5; 95% CI 2.2-50.1), heavy occupational work (OR 9.6; 95% CI 1.3-70.3), anal sphincter lacerations (OR 4.5; 95% CI 1.0-20.0), PFM strength (OR 7.5; 95% CI 1.5-36.4) and endurance (OR 11.5; 95% CI 2.0-66.9) were independently related to POP.
Body mass index, socioeconomic status, heavy occupational work, anal sphincter lacerations and PFM function were independently associated with POP, whereas joint mobility and physical activity were not.
探讨盆腔器官脱垂（POP）的危险因素，包括体力活动、临床测量的关节活动度和盆底肌肉（PFM）功能。
一对一年龄和产次匹配的病例对照研究。
挪威阿克什胡斯大学医院和一家门诊物理治疗诊所。
从社区妇科医生和报纸广告中招募了 49 名 POP 患者（POP 量化，分期>或=II）和 49 名对照（分期 0 和 I）。
使用经过验证的问卷、访谈和临床检查，包括 Beighton 评分系统（关节过度活动）和阴道压力传感器测量（PFM 功能）。使用一对一匹配病例对照研究的单变量和多变量条件逻辑回归分析，并报告比值比及其 95%置信区间。
盆底肌肉功能（力量、耐力和静息压力）、社会经济地位、体重指数、重体力劳动、体力活动、家族史、产科因素和结缔组织薄弱标志物（妊娠纹、静脉曲张、瘀伤、腹直肌分离、关节过度活动）。
两组在绝经状态、当前吸烟、当前低强度运动、分娩类型（剖宫产、产钳、真空）、出生体重、妊娠纹、腹直肌分离和关节过度活动的发生率方面无显著差异。体重指数（OR 5.0；95%CI 1.1-23.0）、社会经济地位（OR 10.5；95%CI 2.2-50.1）、重体力劳动（OR 9.6；95%CI 1.3-70.3）、肛门括约肌撕裂（OR 4.5；95%CI 1.0-20.0）、PFM 力量（OR 7.5；95%CI 1.5-36.4）和耐力（OR 11.5；95%CI 2.0-66.9）与 POP 独立相关。
体重指数、社会经济地位、重体力劳动、肛门括约肌撕裂和 PFM 功能与 POP 独立相关，而关节活动度和体力活动则不相关。
