What does the report of the USMHRP Phase III study in Thailand mean for HIV and for vaccine developers?
作者信息
Graham Barney S
机构信息
Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
出版信息
Clin Exp Immunol. 2009 Dec;158(3):257-9. doi: 10.1111/j.1365-2249.2009.04055.x.
Abstract
摘要
相似文献
1
What does the report of the USMHRP Phase III study in Thailand mean for HIV and for vaccine developers?美国军事医学研究与物资司令部（USMHRP）在泰国进行的三期研究报告对艾滋病病毒（HIV）及疫苗研发人员意味着什么？
Clin Exp Immunol. 2009 Dec;158(3):257-9. doi: 10.1111/j.1365-2249.2009.04055.x.
2
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Outstanding questions on HIV vaccine trial.关于HIV疫苗试验的悬而未决的问题。
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Support for the RV144 HIV vaccine trial.对RV144艾滋病疫苗试验的支持。
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Public health. A sound rationale needed for phase III HIV-1 vaccine trials.公共卫生。HIV-1疫苗三期试验需要合理依据。
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Thai HIV vaccine trial prompts angry exchanges.泰国艾滋病疫苗试验引发激烈争论。
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Controversial HIV vaccine enters phase III trials amid skepticism.备受争议的艾滋病疫苗在质疑声中进入三期试验。
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Translational Mini-Review Series on Vaccines for HIV: Harnessing innate immunity for HIV vaccine development.艾滋病疫苗转化研究迷你综述系列：利用固有免疫研发艾滋病疫苗
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Translational Mini-Review Series on Vaccines for HIV: T lymphocyte trafficking and vaccine-elicited mucosal immunity.艾滋病疫苗转化研究迷你综述系列：T淋巴细胞转运与疫苗诱导的黏膜免疫
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Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1.炎症性生殖器感染减轻了A和C亚型HIV-1异性传播中的严重基因瓶颈。
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Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial.一种细胞介导免疫HIV-1疫苗的疗效评估（STEP研究）：一项双盲、随机、安慰剂对照的概念验证试验。
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25 years of HIV research on virology, virus restriction, immunopathogenesis, genes and vaccines.25年的HIV病毒学、病毒限制、免疫发病机制、基因及疫苗研究
Clin Exp Immunol. 2008 Oct;154(1):6-14. doi: 10.1111/j.1365-2249.2008.03750.x. Epub 2008 Aug 29.
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Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.一项关于HIV-1金丝雀痘疫苗（vCP1452）单独使用及与重组gp120联合使用的2期研究：阴性结果未能引发3期相关试验。
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Attenuated poxvirus-based simian immunodeficiency virus (SIV) vaccines given in infancy partially protect infant and juvenile macaques against repeated oral challenge with virulent SIV.婴儿期接种的基于减毒痘病毒的猴免疫缺陷病毒（SIV）疫苗可部分保护幼年猕猴免受强毒SIV的反复口服攻击。
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Augmentation of human immunodeficiency virus type 1 neutralizing antibody by priming with gp160 recombinant vaccinia and boosting with rgp160 in vaccinia-naive adults. The NIAID AIDS Vaccine Clinical Trials Network.在未感染过牛痘的成年人中，先用重组牛痘病毒gp160进行初免，再用rgp160进行加强免疫，以增强1型人类免疫缺陷病毒中和抗体。美国国立过敏与传染病研究所艾滋病疫苗临床试验网络。
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The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial.叠氮胸苷（AZT）治疗艾滋病及艾滋病相关综合征患者的疗效。一项双盲、安慰剂对照试验。
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