警惕慢性炎症性肠病背景下发生癌症时的PET-CT结果

[Beware of PET-CT results in cases of cancer occurring in the setting of chronic inflammatory bowel disease].

作者信息

Bonaventure T, Goéré D, Boige V, Pocard M

机构信息

Département médico-chirurgical de pathologie digestive, hôpital Lariboisière, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France.

出版信息

J Chir (Paris). 2009 Dec;146(6):579-82. doi: 10.1016/j.jchir.2009.10.006. Epub 2009 Nov 10.

DOI:10.1016/j.jchir.2009.10.006

PMID:19906376

Abstract

PET-CT scanning has been proposed as part of the pre-treatment evaluation of GI cancers with equivocal radiologic findings. PET-CT has also been prosposed for the evaluation of patients with chronic inflammatory bowel disease (IBD). We report the case of a patient with IBD and a new diagnosis of rectal cancer; PET-CT overestimated the degree of tumor extension due to false-positive increased uptake in areas of chronic inflammation from IBD. This observation underlines the need for cautious interpretation of PET-CT results for cancer in patients with associated inflammatory illness.

摘要

正电子发射断层扫描-计算机断层扫描（PET-CT）已被提议作为胃肠道癌症放射学检查结果不明确时的预处理评估的一部分。PET-CT也已被提议用于评估慢性炎症性肠病（IBD）患者。我们报告了一例患有IBD且新诊断为直肠癌的患者；由于IBD慢性炎症区域出现假阳性摄取增加，PET-CT高估了肿瘤的扩展程度。这一观察结果强调了对伴有炎症性疾病的癌症患者的PET-CT结果进行谨慎解读的必要性。