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2009 年甲型 H1N1 流感大流行:普通儿科人群中的临床表现谱。

Pandemic (H1N1) 2009: a clinical spectrum in the general paediatric population.

机构信息

Gold Coast Hospital, Queensland, Australia.

出版信息

Arch Dis Child. 2011 Jan;96(1):96-8. doi: 10.1136/adc.2009.176859. Epub 2009 Nov 10.

DOI:10.1136/adc.2009.176859
PMID:19906639
Abstract

This retrospective case series describes the clinical spectrum of 43 children with pandemic (H1N1) 2009 admitted to a single hospital in Australia during the peak winter flu season. Clinical features, diagnoses, length of hospitalisation and complications were reviewed in children up to 17 years of age with proven pandemic (H1N1) 2009 by RT-PCR. The median age was 6 years, 42% had a pre-existing medical condition. The most common presentation was fever and cough, and 88% of patients met our criteria for flu-like illness. Consolidation on chest x ray was the most common diagnosis (n=20, 46%), followed by dehydration (n=13, 30%). Three (7%) had encephalopathy and two (5%) had diabetic ketoacidosis. There were two intensive care admissions and no deaths. Pandemic (H1N1) 2009 flu has a wide range of presentation in the paediatric population. The diagnosis should be considered during the current pandemic in any child with fever, or who is unwell.

摘要

本回顾性病例系列描述了在澳大利亚一个单一医院的流感高发冬季期间,43 名感染大流行(H1N1)2009 的儿童的临床特征。对通过 RT-PCR 确诊的 17 岁以下大流行(H1N1)2009 儿童的临床特征、诊断、住院时间和并发症进行了回顾。中位年龄为 6 岁,42%有既往疾病。最常见的表现是发热和咳嗽,88%的患者符合我们流感样疾病的标准。胸部 X 线片上的实变是最常见的诊断(n=20,46%),其次是脱水(n=13,30%)。3 例(7%)有脑病,2 例(5%)有糖尿病酮症酸中毒。有 2 例患者收入重症监护病房,无死亡病例。大流行(H1N1)2009 流感在儿科人群中有广泛的表现。在当前大流行期间,任何发热或不适的儿童都应考虑诊断。

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