Homma Shinji, Mashima Ichiro, Muramatsu Yoshiyuki, Gejyo Fumitake
Division of Physiology II, Faculty of Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata City, Niigata 950-2076, Japan.
J Smooth Muscle Res. 2009 Oct;45(5):209-16. doi: 10.1540/jsmr.45.209.
The respiratory rate, LF, HF, and the LF/HF ratio from heart rate variability (HRV) were compared between outpatients (n=25) and controls (n=58) during rest and while performing a mirror drawing test (MDT). Anxiety and depression scores were obtained before the test. In addition, the power content of the electrogastrograms (EGGs) recorded during MDT were compared to those recorded during rest (c-MDT/r). The anxiety scores, depression scores, resting heart rate, resting respiratory rate and the 3 cpm resting frequency of the epigastric EGG were significantly higher in outpatients than in controls. Both the heart rate and the 3 cpm frequency in the infraumbilical EGG during the stress of the MDT were significantly higher in outpatients than in controls. Instability factors (IF, standard deviation/mean frequency) of the 3 cpm frequency in the epigastric EGG were higher in controls than in outpatients, though the spectral frequencies were similar and insignificantly different between the two groups. Interestingly, the slope of the significant linear correlation was positive in controls but was negative in outpatients between both the resting LF/HF and the power content ratio of the 3 cpm frequency in the infraumbilical EGG, c-MDT/r, which corresponds to the colonic responses to MDT stress.
在静息状态以及进行镜像绘图测试(MDT)期间,比较了门诊患者(n = 25)和对照组(n = 58)的呼吸频率、低频(LF)、高频(HF)以及心率变异性(HRV)中的LF/HF比值。在测试前获取焦虑和抑郁评分。此外,还比较了MDT期间记录的胃电图(EGG)的功率成分与静息期间记录的功率成分(c-MDT/r)。门诊患者的焦虑评分、抑郁评分、静息心率、静息呼吸频率以及上腹部EGG的3次/分钟静息频率均显著高于对照组。在MDT应激期间,门诊患者脐下EGG的心率和3次/分钟频率均显著高于对照组。上腹部EGG的3次/分钟频率的不稳定因素(IF,标准差/平均频率)在对照组中高于门诊患者,尽管两组之间的频谱频率相似且差异不显著。有趣的是,静息LF/HF与脐下EGG的3次/分钟频率的功率成分比值(c-MDT/r)之间的显著线性相关斜率在对照组中为正,而在门诊患者中为负,这与结肠对MDT应激的反应相对应。