子宫动脉多普勒在子痫前期患者中的预测作用。
Prognostic role of uterine artery Doppler in patients with preeclampsia.
机构信息
Department of Maternal-Fetal Medicine, ICGON, Fetal and Perinatal Medicine Research Group and Center of Biomedical Research on Rare Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain.
出版信息
Fetal Diagn Ther. 2010;27(1):8-13. doi: 10.1159/000258048. Epub 2009 Nov 11.
OBJECTIVES
To evaluate the predictive capacity of umbilical, cerebral and uterine artery Doppler in women admitted for preeclampsia (PE).
METHODS
190 consecutive singleton pregnancies admitted with PE were included. Umbilical, cerebral and uterine artery Dopplers were performed. The association with adverse perinatal outcome was evaluated from 2 x 2 tables and multivariately by logistic regression.
RESULTS
A total of 82 (43%) women had an abnormal uterine artery Doppler on admission, being more prevalent in early-onset (<32 weeks) than in the late-onset PE (62 vs. 27%, p < 0.05). In both early- and late-onset forms, uterine artery Doppler showed a greater capacity than umbilical and middle cerebral artery Doppler for predicting adverse perinatal outcome.
CONCLUSION
Uterine artery Doppler was the best predictive parameter for perinatal outcome in pregnancies with PE and may be included as a primary surveillance test.
目的
评估在子痫前期（PE）患者中进行脐动脉、大脑中动脉和子宫动脉多普勒检查的预测能力。
方法
纳入 190 例连续的单胎妊娠 PE 患者。进行脐动脉、大脑中动脉和子宫动脉多普勒检查。通过 2x2 表和多变量逻辑回归评估与不良围产结局的相关性。
结果
共有 82 名（43%）女性在入院时存在异常的子宫动脉多普勒，早发型（<32 周）比晚发型 PE 更常见（62%比 27%，p<0.05）。在早发型和晚发型中，子宫动脉多普勒对预测不良围产结局的能力均优于脐动脉和大脑中动脉多普勒。
结论
在患有 PE 的孕妇中，子宫动脉多普勒是预测围产结局的最佳参数，可作为首选的监测检查。
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